Results 91 to 100 of about 783,699 (277)
Lipids in Health and DiseaseIntervertebral disc degeneration (IVDD) is the primary cause of low back pain (LBP). Dyslipidaemia can induce a chronic inflammatory state in the body, promote the polarization of macrophages, and may affect the homeostasis of the intervertebral disc (IVD).
Chang, Sheng-Jie +5 more
openaire +2 more sources
Demo 06-01 Angular Acceleration Machine
, 2001 This device illustrates the application of the rotational analog of Newton's second law, t = I a. Two weights can be positioned symmetrically along an arm that rotates in a vertical plane around its center, varying the moment of inertia of the rotating
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Acta Dermato-Venereologica, 2018 Aryl hydrocarbon receptor (AHR) is a chemical sensor that is expressed abundantly in epidermal keratinocytes. Oxidative AHR ligands induce the production of reactive oxygen species.
Masutaka Furue +2 more
doaj +1 more source
Excessive Internet use: Implications for sexual behaviour [PDF]
, 2000 The Internet appears to have become an ever-increasing part in many areas of people’s day-to- day lives. One area that deserves further examination surrounds sexual behavior and excessive Internet usage.
Griffiths, M, Griffiths, MD
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Timescales for detecting a significant acceleration in sea level rise [PDF]
, 2014 There is observational evidence that global sea level is rising and there is concern that the rate of rise will increase, significantly threatening coastal communities.
Pattiaratchi, Charitha B. +9 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Surfatron and stochastic acceleration of electrons in astrophysical plasmas [PDF]
, 2005 Electron acceleration by large amplitude electrostatic waves in astrophysical plasmas is studied using particle-in-cell (PIC) simulations. The waves are excited initially at the electron plasma frequency $\omega_{\rm pe}$ by a Buneman instability driven ...
K. G. McCLEMENTS +9 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source