Results 71 to 80 of about 2,476,077 (311)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Big Ideas Exchange: New Directions for Defense [video]

, 2016
The latest NPS Big Ideas Exchange showcases five NPS speakers that bring forward new and potentially game-changing ideas to address grand challenges in American national security.
Strawser, Bradley, Arquilla, John, Denning, Peter J., Naval Postgraduate School, Lyons, Todd   +4 more
core  

Bitcoin Exchange Software

, 2019
If you are finding best cryptocurrency exchange software Development Company then I suggest you Blockchain Developments. Coinsclone is a cryptocurrency exchange development company that pioneers in developing complete cryptocurrency exchange software to ...
Coinsclone Cryptocurrency Exchange Solution (6021788)
core   +1 more source

Optimizing virtual power plant coordination through locational marginal flexibility under network constraints

Scientific Reports
The transition toward deeply decarbonized energy systems requires optimization frameworks that can simultaneously capture long-term dynamics, operational reliability, and contractual stability while managing multiple forms of uncertainty.
Liye Xie, Guodong Li, Min Xu, Xiaoliang Dong, Zhongfu Tan   +4 more
doaj   +1 more source

The Impact of War and Conflict on People Living with Diabetes: A Scoping Review

Clinical Diabetology
OBJECTIVE: There is substantial literature detailing the interaction between war and conflict on overall human health. However, there is limited understanding of the impact of war and conflict on people living with diabetes. This scoping review describes
Emma Ospelt, Ann Mungmode, Holly Hardison, Anton Wirsch, Nicole Rioles, James Dawson, McKing Amedari, Halis K. Akturk, Viral N. Shah, Nuha El Sayed, Osagie Ebekozien   +10 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Big Ideas Exchange Highlights Struggle for Cyber Advantage [video]

, 2019
Naval Postgraduate School (NPS) faculty and students researching the cutting-edge of how the U.S. can gain an advantage in cyberspace shared their game-changing research during the latest Big Ideas Exchange (BIX), Nov.

core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Big Ideas Exchange -- Coming May 16, 2019 [video]

, 2019
The Big Ideas Exchange (BIX) is our opportunity to share the game-changing research of NPS faculty and students that directly addresses grand challenges in American national security. The next BIX, coming May 16, 2019, at 3:00 p.m.

core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source