Results 51 to 60 of about 2,476,077 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A distributionally robust bilevel optimization model for wholesale–retail electricity market design

open access: yesScientific Reports
The increasing penetration of renewable energy resources and the rising volatility of wholesale electricity prices introduce significant uncertainty into tariff design and retailer procurement decisions.
Xing Jia   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Exchange Club of Toledo, Ohio, membership roster, 1927

open access: yes, 2020
The Exchange Club is a service organization founded in Detroit, Michigan in 1911. This roster from 1927 contains information on members with detailed information on names, home and business addresses, phone numbers, and ...
Exchange Club of Toledo, Ohio (Toledo, Ohio)
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Thermal exchange effects on steel thixoforming processes [PDF]

open access: yes, 2010
Steel thixoforging is an innovative semi-solid forming process. It allows the manufacturing of complex parts and minimises the forming load. This work aims to identify and characterise the main feature zones of a thixoforging part.
LANGLOIS, Laurent   +2 more
core   +1 more source

Decadal Evolution of Atmospheric Sulfate and Nitrate and Its Potential Link to Energy Restructuring: A Case Study in Guangdong Province, China

open access: yesGlobal Challenges
The global shift toward renewable energy and the wide adoption of electric vehicles (EVs) are expected to mitigate a series of global environmental concerns, while few studies have focused on their contribution to reducing PM2.5 concentrations.
Haohao Wang   +4 more
doaj   +1 more source

A bidding data-driven method for collusion identification in centralized power market bidding

open access: yesInternational Journal of Electrical Power & Energy Systems
With the increasing intelligence of the power grid and the deepening reform of the power market, the risk that some market participants violate trading rules and engage in bidding collusion has become increasingly prominent.
Yumin Li   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

New Directions For Defense, A Big Ideas Special Event: The Next Big Bang, with Joseph Hooper [video] [PDF]

open access: yes, 2016
The Big Idea Exchange (BIX)Includes presentation slidesA burning aluminum cube releases much more energy than a detonating TNT cube. What if we could force aluminum to burn very rapidly? Next generation weapons may pack a bigger bang in a smaller package
Naval Postgraduate School   +1 more
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