Results 61 to 70 of about 2,476,077 (311)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Mycenaean Greece and Europe. Interconnections and exchanges in the light of recent research [PDF]

open access: yesStudia Hercynia, 2022
The debate over possible connections between Bronze Age Greece and the rest of the European continent, to which Jan Bouzek made major contributions throughout his career, is reviewed in the light of new con tributions and finds.
Anthony Harding
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Report of the New York Produce Exchange.

open access: yes, 1878
Published with volumes 1887/88-1901/02 of the Annual statistical report of the New York Produce Exchange."With the charter, by-laws, and the several trade rules adopted by the Exchange, and a list of its members.
New York Produce Exchange.
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

U.S. Marine Corps Big Ideas [PDF]

open access: yes, 2018
Capt. Andrea Writt: High Altitude Bal/0011s and Smal/Sats for Space Resilience; Capt. Matthew Audette:Counter Swarm Options; Capt. Adrian Felder: Revolutionizing Tactical Networks with Free Space Optics; Capt.
Felder, Adrian   +5 more
core  

Application of Recombination -Induced Tag Exchange (RITE) to study histone dynamics in human cells

open access: yesEpigenetics, 2020
In eukaryotes, nucleosomes form a barrier to DNA templated reactions and must be dynamically disrupted to provide access to the genome. During nucleosome (re)assembly, histones can be replaced by new histones, erasing post-translational modifications ...
Thom M. Molenaar   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Study Investigating Prevalence of Pain in Horse Riders over Thirty-Five Years Old

open access: yesInternational Journal of Equine Science, 2023
Horse riding is considered to be one of the most dangerous sports, more so than skiing, motor racing, and rugby. A rider will fall, on average, once every two years, and during their career, one in five are seriously injured. Previous research has looked
Victoria Lewis   +3 more
doaj  

An Asymmetrical Trade: Trade in the Exotic and Our Understanding of Axes and Early Neolithic Exchange

open access: yesInternet Archaeology, 2009
This article explores the idea that the movement of axes away from their source of procurement, such as those of Group VI, reflects in part an invisible trade in perishable goods. In particular, it hypothesises that the pattern of movement was stimulated
Tom Clare
doaj   +1 more source

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