Results 51 to 60 of about 3,134,729 (344)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
The “real” exchange rate regime in China since 2015′s exchange rate reform
Asia and the Global Economy, 2023 Moving away from a fixed exchange rate in 2005, China has gradually enlarged the band of fluctuations of Renminbi (RMB) and implemented various reforms on its central parity to have a more flexible exchange rate regime.
Jinzhao Chen
doaj
Bilateral Exchange Rates and Jobs [PDF]
Review of International Economics, 2013 AbstractWe study the labor market effects of realignment in fixed bilateral exchange rates, such as China's peg to the US dollar. We employ the open economy model by de Melo and Robinson to identify the core parameters of the real, trade side of the economy driving the unemployment effects of bilateral exchange rate realignment.
Bekkers, Eddy, Francois, Joseph
openaire +7 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
BANK OF RUSSIA’S EXCHANGE RATE POLICE AND OPTION OF EXCHANGE RATE REGIME
Мир новой экономики, 2018 The article devotes to such issues as the Russian current exchange rate police, the affected to exchange rate regime option factors, currency interventions, and aiming to smoothing extreme exchange rate volatility measures.
VALENTINA VIL’EVNA Kuznetsova
doaj
REAL EXCHANGE RATE VARIABILITY AND THE CHOICE OF EXCHANGE RATE REGIME IN IRAN [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2003 Journal: IRANIAN ECONOMIC RESEARCH Summer 2003 , Volume 5 , Number 15; Page(s) 121 To 141. Paper: REAL EXCHANGE RATE VARIABILITY AND THE CHOICE OF EXCHANGE RATE REGIME IN IRAN Author(s): JABAL AMELI FARKHONDEH*, BARADARAN SHORAKA H ...
Farkhondeh Jabal Ameli +1 more
doaj
Exchange rate regime and real exchange rate behavior [PDF]
This paper examines exchange rate regimes from the viewpoint of the validity of purchasing power parity (PPP). Specifically, we analyze real exchange rate behavior under various classifications of exchange rate arrangement through panel unit root tests ...
Harutaka Murofushi +2 more
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