Results 61 to 70 of about 15,697,759 (397)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The impact of exchange rates on stock market performance of the Emerging 7 [PDF]
Doaa El-Diftar
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
REAL EXCHANGE RATE VARIABILITY AND THE CHOICE OF EXCHANGE RATE REGIME IN IRAN [PDF]
Journal: IRANIAN ECONOMIC RESEARCH Summer 2003 , Volume 5 , Number 15; Page(s) 121 To 141. Paper: REAL EXCHANGE RATE VARIABILITY AND THE CHOICE OF EXCHANGE RATE REGIME IN IRAN Author(s): JABAL AMELI FARKHONDEH*, BARADARAN SHORAKA H ...
Farkhondeh Jabal Ameli +1 more
doaj
Türkiye has implemented different exchange rate regimes and foreign trade policies throughout its 100-year history. The foreign trade deficit has been a persistent issue since the establishment of the free-market economy and its opening to foreign ...
Atiye Beyhan Akay
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Analysis of Heat Exchange Rate for Low-Depth Modular Ground Heat Exchanger through Real-Scale Experiment [PDF]
Kwonye Kim +5 more
openalex +1 more source
Capital Inflows and Real Exchange Rate Appreciation in Latin America: The Role of External Factors
The characteristics of recent capital inflows to Latin America are discussed. It is argued that these inflows are partially explained by economic conditions outside the region, like the recession in the United States and lower international interest ...
G. Calvo +2 more
semanticscholar +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

