Results 51 to 60 of about 36,537 (181)
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa+3 more
core +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Abstract In most blood supply chains, blood centers and hospitals make individual decisions, resulting in an inefficient structure of the blood supply chain, which in turn renders supply and demand matching a challenging exercise. In this work, we make the very first attempt to optimize the interaction between blood centers and hospitals.
Mohammad S. Moshtagh+2 more
wiley +1 more source
Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]
Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle+7 more
core +2 more sources
Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz+4 more
wiley +1 more source
Modelling very large complex systems using distributed simulation: A pilot study in a healthcare setting [PDF]
Modern manufacturing supply chains are hugely complex and like all stochastic systems, can benefit from simulation. Unfortunately supply chain systems often result in massively large and complicated models, which even today’s powerful computers cannot ...
Brailsford, S+3 more
core +1 more source
ABSTRACT We present a neonate born to a mother with a known diagnosis of cutaneous polyarteritis nodosa (cPAN) who presented with acrocyanosis on the first day of life, which progressed to livedo reticularis and eventual digital necrosis and autoamputation.
Marin P. Melloy, Sheilagh Maguiness
wiley +1 more source
The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs [PDF]
The correction of hypovolemia with acellular fluids results in acute normovolemic anemia. Whether the choice of the infusion fluid has an impact on the maintenance of oxygen (O2) supply during acute normovolemic anemia has not been investigated so far ...
Habler, Oliver+7 more
core +2 more sources
“In this observational study of 257 EBV‐mismatched (EBV D+/R−) adult and pediatric solid organ transplant (SOT) recipients, we investigate the incidence and timing of whole blood EBV DNAemia as well as associations between donor‐acquired EBV DNAemia and donor and recipient age, and organ transplanted to provide evidence to optimize post‐transplant EBV ...
Catherine Burton+2 more
wiley +1 more source