Results 51 to 60 of about 56,972 (200)

Outcomes following kidney transplantation in patients with sickle cell disease: The impact of automated exchange blood transfusion

open access: yesPLoS ONE, 2020
There are over 12,000 people with sickle cell disease (SCD) in the UK, and 4–12% of patients who develop Sickle Cell Nephropathy (SCN) progress to End Stage Renal Disease (ESRD).
J. Willis   +12 more
semanticscholar   +1 more source

Stewardship of Prehospital Low Titer O-Positive Whole Blood in a Large Urban Fire-Based EMS System

open access: yesPrehospital Emergency Care, 2021
Introduction: Trauma is the leading cause of death for those aged 1 to 46 years with most fatalities resulting from hemorrhage prior to arrival to hospital.
W. Bullock   +5 more
semanticscholar   +1 more source

The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs [PDF]

open access: yes, 2012
The correction of hypovolemia with acellular fluids results in acute normovolemic anemia. Whether the choice of the infusion fluid has an impact on the maintenance of oxygen (O2) supply during acute normovolemic anemia has not been investigated so far ...
Habler, Oliver   +7 more
core   +2 more sources

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

open access: yesAdvanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab   +8 more
wiley   +1 more source

Cholesterol exchange and synthesis in the live rat.

open access: yesJournal of Lipid Research, 1985
The turnover of plasma cholesterol and de novo cholesterol synthesis were measured simultaneously in the live rat, immediately after administration of [3H]water together with a large volume exchange transfusion of whole blood prelabeled with [14C ...
S J Robins   +3 more
doaj   +1 more source

Effect of Red Blood Cell Transfusion on Inflammatory and Angiogenic Pathways in Patients With Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is a chronic inflammatory state, characterized by increased plasma values of inflammatory and angiogenic proteins. Although red blood cell (RBC) transfusion is known to have immunomodulatory effects in other conditions, its potential effects on the inflammatory state in SCD remain largely unknown.
Lydian A. de Ligt   +9 more
wiley   +1 more source

The Rhesus Factor and Disease Prevention [PDF]

open access: yes, 2004
First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004. ©The Trustee of the Wellcome Trust, London, 2004. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated ...
Christie, DA, Tansey, EM, Zallen, DT
core  

Coexisting Sickle Cell Anemia and Sarcoidosis: A Management Conundrum! [PDF]

open access: yes, 2017
Sickle cell disease and Sarcoidosis are conditions that are more common in the African American population. In this report we share an unfortunate patient who had hepatic sarcoidosis but could not receive steroids since that precipitated acute liver ...
Gollahalli, Nagesh S., Nutan, FNU
core   +3 more sources

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

open access: yesBiotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Longitudinal changes in peritoneal solute transport rate and the impact of lower glucose degradation product glucose dialysates

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 471-478, June 2025.
Abstract Introduction Peritoneal solute transfer rates (PSTR) are reported to increase with time. Changes in PSTR were reviewed in long‐term peritoneal dialysis (PD) patients to determine whether lower glucose degradation products (low GDP) dialysates prevented an increase in PSTR. Methods PSTR was determined with a 4‐h peritoneal equilibrium test with
Andrew Davenport
wiley   +1 more source

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