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Feasibility of a drug allergy registry-based excipient allergy database and call for universal mandatory drug ingredient disclosure: the case of PEG [PDF]
Frontiers in AllergyBackgroundExcipient allergy is a rare, but potentially lethal, form of drug allergy. Diagnosing excipient allergy remains difficult in regions without mandatory drug ingredient disclosure and is a significant barrier to drug safety.ObjectiveTo ...
Andy Ka Chun Kan +4 more
doaj +2 more sources
Excipient Nanoemulsions for Improving Oral Bioavailability of Bioactives
Nanomaterials, 2016 The oral bioavailability of many hydrophobic bioactive compounds found in natural food products (such as vitamins and nutraceuticals in fruits and vegetables) is relatively low due to their low bioaccessibility, chemical instability, or poor absorption ...
Laura Salvia Trujillo +2 more
exaly +3 more sources
Achieving High Excipient Efficiency with Elastic Thermoplastic Polyurethane by Ultrasound Assisted Direct Compression [PDF]
, 2019 Ultrasound assisted compression (USAC) is a manufacturing technique which applies thermal and mechanical energy to the powder bed, producing tablets with improved characteristics compared to the direct compression process.
Caraballo Rodríguez, Isidoro +2 more
core +3 more sources
Comparative analysis of co-processed starches prepared by three different methods [PDF]
British Journal of Pharmacy, 2017 Co-processing is currently of interest in the generation of high-functionality excipients for tablet formulation. In the present study, comparative analysis of the powder and tableting properties of three co-processed starches prepared by three different
Yonni Apeji +6 more
doaj +6 more sources
A Platform Approach to Protein Encapsulates with Controllable Surface Chemistry
Molecules, 2022 The encapsulation of proteins into core-shell structures is a widely utilised strategy for controlling protein stability, delivery and release. Despite the recognised utility of these microstructures, however, core-shell fabrication routes are often too ...
Nina Warner +4 more
doaj +1 more source
An Overview of the Stability and Delivery Challenges of Commercial Nucleic Acid Therapeutics
Pharmaceutics, 2023 Nucleic acid (NA)-based biopharmaceuticals have emerged as promising therapeutic modalities. NA therapeutics are a diverse class of RNA and DNA and include antisense oligonucleotides, siRNA, miRNA, mRNA, small activating RNA, and gene therapies ...
Rahul G. Ingle, Wei-Jie Fang
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Pharmaceutics, 2022 Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years.
Angel J. Castañeda Ruiz +6 more
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Pharmacoepidemiology, 2023 Propylene glycol (PG) and benzyl alcohol (BA) have been shown to inhibit the metabolizing enzyme for acetaminophen in the liver. Ethanol has unpredictable effects on acetaminophen metabolism.
Kannan Sridharan, Muna Al Jufairi
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Foods, 2022 The recent growing interest in lactose intolerance has resulted in the proliferation of lactose-free products by food manufacturing companies. Since updated papers about lactose and its uses are missing, the main purpose of this review is to investigate ...
Simona Dominici +7 more
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On the role of excipients and their future development [PDF]
BIO Web of Conferences, 2023 Excipients are inactive substances that are included in pharmaceutical formulations alongside active ingredients. These substances are added to pharmaceutical products for various purposes, including improving stability, enhancing bioavailability, aiding
Li Zinan
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