Vehicles for Drug Delivery and Cosmetic Moisturizers: Review and Comparison
Pharmaceutics, 2021 Many dermatological conditions, such as eczema and psoriasis, are treated with topical therapeutic products. Instead of applying the active drug directly onto the skin, it is combined with a vehicle to aid in its delivery across the stratum corneum (SC ...
Tanya M. Barnes +4 more
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Pharmaceutics, 2020 The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated.
Ionuț Ledeți +11 more
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Interactions and incompatibilities between the active ingredient and the excipient [PDF]
Farmacja Polska, 2021 Excipients are important components of the final medicinal product. They perform many important functions as fillers, lubricants, disintegrating agents, stabilizers, emulsifiers, etc., and their presence in the formulation is essential.
Ewelina Mundzik-Janczarska +1 more
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Evaluation of Pharmaceutical Compatibility between Acarbose and Common Excipients Used in the Development of Controlled Release Formulations [PDF]
Pharmaceutical Sciences, 2021 Background: Excipients are used in the formulation of pharmaceutical dosage forms, but mayinteract with active pharmaceutical ingredients (APIs). Some of these interactions could alterthe physicochemical properties of the APIs which can affect the ...
Aiesheh Gholizadeh-Hashjin +2 more
doaj +1 more source
Frontiers in Immunology, 2022 Unintended immunogenicity can affect the safety and efficacy of therapeutic proteins and peptides, so accurate assessments of immunogenicity risk can aid in the selection, development, and regulation of biologics. Product- and process- related impurities
Seth G. Thacker +6 more
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A 3D printed drug delivery implant formed from a dynamic supramolecular polyurethane formulation [PDF]
, 2020 Using a novel molecular design approach, we have prepared a thermo-responsive supramolecular polyurethane as a matrix material for use in drug eluting implants.
Clark, E. A. +10 more
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Predicting the Drug Release Kinetics of Matrix Tablets [PDF]
, 2009 In this paper we develop two mathematical models to predict the release kinetics of a water soluble drug from a polymer/excipient matrix tablet. The first of our models consists of a random walk on a weighted graph, where the vertices of the graph ...
Baeumer, Boris +5 more
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Application of Texture Analysis technique in formulation development of lyophilized orally disintegrating tablets containing mannitol, polyvinylpyrrolidone and amino acids [PDF]
, 2018 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Orally disintegrating tablets (ODTs) attract a great attention as this easy swallowing dosage form often ...
Ermolina, I., Hackl, E. V.
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Formulation pre-screening of inhalation powders using computational atom-atom systematic search method [PDF]
, 2014 This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.The synthonic modeling approach provides ...
Collins, Elizabeth +10 more
core +4 more sources
The use of high performance anion exchange chromatography for the detection of counterfeit pharmaceutical products using the excipient content as a marker [PDF]
, 2015 The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients.
Beasley, Emma +2 more
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