Results 111 to 120 of about 53,055 (281)

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

open access: yesBMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang   +5 more
wiley   +1 more source

Evaluation of Mucilages Isolated from Seeds of Hyptis suaveolens, Salvia hispanica and Linum usitatissimum as Pharmaceutical Excipients in Solid and Liquid Formulations [PDF]

open access: yes, 2018
In this work, we have evaluated the performance of mucilages from seeds of Hyptis suaveolens, Linum usitatissimum and Salvia hispanica as stabilizers in liquid formulations and as binders and disintegrants in solid pharmaceutical forms.
Jeanina Alfaro   +4 more
core   +2 more sources

A Thermal-Analysis-Technique-Based Mechanistic Approach toward the Release of Omeprazole from Solid Dosage Forms

open access: yesScientia Pharmaceutica
The design, development, and release kinetics of omeprazole (OME) from solid dosage forms have been investigated. These formulations were examined for their resilience in pH = 4.5 buffer solutions and their rate of disintegration in a small-intestine ...
Georgios Agapakis   +4 more
doaj   +1 more source

The Journal of Excipients and Food Chemicals: Not just ‘yet another e-journal’ [PDF]

open access: yes, 2016
The quality of a scientific e-journal depends on the pool of knowledge, expertise, commitment and passion of its founders and editorial advisory board members and on the rigor of its peer review process.
Shireesh Apte
core  

Tailoring drug‐to‐lipid ratio in redox‐responsive lipid‐mimetic prodrug liposomes for superior cabazitaxel delivery and antitumor efficacy

open access: yesBMEMat, EarlyView.
Redox‐responsive lipid‐mimetic prodrug liposomes with high drug‐to‐lipid ratios enhance cabazitaxel delivery, prolong circulation, and enable tumor‐selective drug release for superior antitumor efficacy and safety. Abstract Liposomes represent one of the most extensively investigated nanocarriers in drug delivery.
Shengyao Xu   +16 more
wiley   +1 more source

Impact of Polyvinylpyrrolidone-Vinyl Acetate Copolymer and Sodium Starch Glycolate Excipients on Phenolic Extraction from Red Clover: Enhancing Biological Activity and Antioxidant Potential

open access: yesPharmaceutics
Adding certain excipients during the extraction process can enhance the concentration of target compounds, leading to potentially increased biological properties of the plant extract.
Jurga Andreja Kazlauskaite   +2 more
doaj   +1 more source

The potential of excipients to improve the efficiency of immuno-oncology therapy. [PDF]

open access: yes
The cocktail of substances used in cell culture media to cryopreserve, transfect, grow, expand, fractionate, concentrate, wash and remove impurities from leukapheresis harvested T-cells are functional excipients.
Shireesh Apte
core   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

open access: yesBiotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan   +3 more
wiley   +1 more source

EXCIPIENTS IN ORAL SUSPENSIONS

open access: yesРазработка и регистрация лекарственных средств, 2019
The article describes the approaches to classification and separation of groups of excipients in oral suspensions of both domestic and foreign authors. A number of existing classifications of excipients for oral suspensions are presented. The analysis of
V. V. Vernikovsky, E. V. Tretyakova
doaj  

Quantification of clarithromycin polymorphs in presence of tablet excipients. [PDF]

open access: yes, 2014
Excipients can cause a considerable challenge when developing a solid form of an active pharmaceutical ingredient (API). The aim of this present study was to analyze the polymorphs of clarithromycin (CAM) mixed with excipients using powder X-ray ...
Arvind Kumar Bansal   +5 more
core  

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