Results 31 to 40 of about 453,414 (314)

Serum factors create species-specific barriers to hepatic gene transfer by lipid nanoparticles in liver-humanized mice

open access: yesMolecular Therapy: Methods & Clinical Development
Lipid nanoparticles (LNPs) can efficiently deliver nucleic acid therapeutics to a range of tissues, particularly hepatocytes to treat diseases of the liver.
Daniel Stone   +10 more
doaj   +1 more source

Jumping Ahead with Sleeping Beauty: Mechanistic Insights into Cut-and-Paste Transposition

open access: yesViruses, 2021
Sleeping Beauty (SB) is a transposon system that has been widely used as a genetic engineering tool. Central to the development of any transposon as a research tool is the ability to integrate a foreign piece of DNA into the cellular genome.
Matthias T. Ochmann, Zoltán Ivics
doaj   +1 more source

Excision in algebraic K-theory revisited [PDF]

open access: yes, 2018
By a theorem of Suslin, a Tor-unital (not necessarily unital) ring satisfies excision in algebraic K-theory. We give a new and direct proof of Suslin's result based on an exact sequence of categories of perfect modules.
Tamme, Georg
core   +1 more source

Oral Mucocele Case Series: A Review of Surgical Options and Clinical Findings

open access: yesJournal of Primary Care Dentistry and Oral Health
Mucocele, a benign lesion on the lower lip that is often caused by lip-biting habit and local trauma, is a frequent oral lesion in children. Anxiety is a common psychological condition that drives lip-biting behavior.
Manisha Chaudhary, Akash Kumar Giri
doaj   +1 more source

Ophthalmic masquerades of the atherosclerotic carotids

open access: yesIndian Journal of Ophthalmology, 2014
Patients with carotid atherosclerosis can present with ophthalmic symptoms. These symptoms and signs can be due to retinal emboli, hypoperfusion of the retina and choroid, opening up of collateral channels, or chronic hypoperfusion of the globe (ocular ...
Anupriya Arthur   +4 more
doaj   +1 more source

A Surprise Visitor at Cesarean Section: Gastrointestinal Stromal Tumor of the Uterus

open access: yesMiddle East Journal of Cancer, 2020
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that almost always arise from the GI tract and account for 0.1-3% of GI tumors. During pregnancy, GIST is highly unusual given the predilection of this tumor to appear in the fifth to ...
Simon Raif Marcos   +5 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

Robot-assisted excision with intervertebral foramen endoscopy in the treatment of osteoid osteoma of femoral neck: a case report

open access: yesFrontiers in Pediatrics
BackgroundThe diaphyseal or metaphyseal of the long bone is a common location for osteoid osteoma(OO), however, the femoral neck lesion is rare. There proves an original method to treat this disease.Case presentationAn 11-year-old female, complained of a
Jinying Lao   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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