Results 41 to 50 of about 453,414 (314)

Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype

open access: yes, 2009
Nucleotide excision repair (NER) is responsible for repairing bulky helix-distorting DNA lesions and is essential for the maintenance of genomic integrity.
Mathers, John   +6 more
core   +1 more source

Case report: Combination technique of balloon dilation, membrane excision, and topical mitomycin C for the treatment of nasopharyngeal stenosis in a cat

open access: yesFrontiers in Veterinary Science
A two-year-old neutered male Turkish Angora cat presented with respiratory signs, including chronic snoring sounds and dyspnea with open-mouth breathing. Nasopharyngeal stenosis (NPS) was diagnosed based on endoscopy and computed tomography (CT).
Ho Hyun Kwak   +4 more
doaj   +1 more source

Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

open access: yesViruses, 2010
HIV-1 Reverse Transcriptase (HIV-1 RT) has been the target of numerous approved anti-AIDS drugs that are key components of Highly Active Anti-Retroviral Therapies (HAART).
Stefan G. Sarafianos   +4 more
doaj   +1 more source

Surgical aspects of the treatment of epithelial pilonidal cyst: from primary sources to the present (a review of literature)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2022
To date, surgical treatment of the pilonidal disease (PD), despite the variety of proposed methods, remains an extremely urgent problem. PD is an inflammatory process of the soft tissues of the coccygeal region, which, along with a decrease in the ...
K.I. Sergatskiy   +5 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Submandibular Gland Excision: Analysis of 43 Cases

open access: yes, 2014
Aim: To retrospectively evaluate indications for surgery, histopathological results and surgery complications in patients who underwent submandibular gland excision.
Bayram Veyseller   +6 more
core   +1 more source

Early Onset Basal Cell Carcinoma: Surgical Approach

open access: yesActa Medica Bulgarica, 2014
Basal cell carcinoma (BCC) is the most frequent non-melanoma skin cancer. Only 5-15% of BCC cases can be found in patients aged 20-40 years (so-called early onset).
Betekhtin M.   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

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