Results 201 to 210 of about 144,668 (268)

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Modulation of corticospinal excitability and muscle synergies during visuomotor locomotor task in individuals with and without cerebral palsy: a TMS and EMG study. [PDF]

Front Neurol
Cherni Y, Ghislieri M, Bouyer L, Mercier C.   +3 more
europepmc   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

Drug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe, Marilyn Huestis, Daniel Wang, Thomas Hudzik, John Bothmer, Jack Henningfield   +5 more
wiley   +1 more source

Blood-catalyzed n-doped polymers for reversible optical neural control. [PDF]

Science
Samal S, Xiao S, Nelson S, Kolhe O, Khan HF, Matin MH, Lee WJ, Ahmed M, Wang D, Wang T, Pikes T, Scott AN, Rodriguez JA, Olson MR, Deng Q, Parkinson EI, Rochet JC, Jayant K, Mei J.   +18 more
europepmc   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

Deep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu, Dawei Cui, Yingjie Liu, Yuntao Liang, Yue Zhang   +4 more
wiley   +1 more source

Inhibitory Circuits of the Sensorimotor Network are Not Modulated By Cerebellar Transcranial Direct Current Stimulation in Isolated Cervical Dystonia. [PDF]

Cerebellum
Peemöller F, Grimm K, Rashedi R, Gelderblom M, Zittel S.   +4 more
europepmc   +1 more source

Emotion Regulation as a Predictor of Body Dissatisfaction in Individuals With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Body dissatisfaction (BD) plays a key role in the development and maintenance of eating disorders (EDs). BD might be influenced by emotion regulation. The maladaptive emotion regulation strategy suppression, aimed at inhibiting emotional responses, may increase BD by intensifying negative body‐related affect. Adaptive strategies like
Eline S. J. de Rijk, Alexandra E. Dingemans, Eric F. van Furth, Margarita C. T. Slof‐Op 't Landt   +3 more
wiley   +1 more source

Stratification of Motor Cortex Excitability to Transcranial Stimulation Uncovers Functional Network Differences in Healthy Older Adults as Revealed by Resting State EEG Functional Coupling in Brain Network. [PDF]

Compr Physiol
Nucci L, Frasca F, Pappalettera C, Ginatempo F, Loi N, Ventura L, Zeroual M, Rossini PM, Deriu F, Vecchio F.   +9 more
europepmc   +1 more source

Disordered Eating Behaviors Among U.S. Children With Neuropsychiatric Conditions: A Nationally Representative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study documented associations between parent‐reported disordered eating behaviors and co‐occurring anxiety, depression, behavioral/conduct problems, and attention‐deficit/hyperactivity disorder (ADHD) among U.S. children. Method Data were obtained from the combined 2022–2023 National Survey of Children's Health.
Myriam Casseus
wiley   +1 more source