Results 101 to 110 of about 1,901,818 (345)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Dynamical Manipulation of Surface Plasmon Polaritons

open access: yesApplied Sciences, 2019
As the fundamental and promising branch of nanophotonics, surface plasmon polaritons (SPP) with the ability of manipulating the electromagnetic field on the subwavelength scale are of interest to a wide spectrum of scientists.
Sen Wang, Chunying Zhao, Xing Li
doaj   +1 more source

Multi-dimensional laser spectroscopy of exciton-polaritons with spatial light modulators

open access: yes, 2011
We describe an experimental system that allows one to easily access the dispersion curve of exciton-polaritons in a microcavity. Our approach is based on two spatial light modulators (SLM), one for changing the excitation angles (momenta), and the other ...
Forchel, A.   +8 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dephasing of quantum dot exciton polaritons in electrically tunable nanocavities

open access: yes, 2009
We experimentally and theoretically investigate dephasing of zero dimensional microcavity polaritons in electrically tunable single dot photonic crystal nanocavities.
A. Laucht   +7 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Corrigendum: Dissipative Magnetic Soliton in a Spinor Polariton Bose–Einstein Condensate

open access: yesFrontiers in Physics, 2022
Chunyu Jia   +7 more
doaj   +1 more source

Bidirectional Regulation of GABAA Reversal Potential in the Adult Brain: Physiological and Pathological Implications

open access: yesLife
In physiological conditions, the intracellular chloride concentration is much lower than the extracellular. As GABAA channels are permeable to anions, the reversal potential of GABAA is very close to that of Cl−, which is the most abundant free anion in ...
Haram R. Kim, Marco Martina
doaj   +1 more source

Excitation and ionization processes of Pyridine molecule induced by low-energy electron impact

open access: gold, 2021
Ján Blaško   +4 more
openalex   +1 more source

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