Results 101 to 110 of about 371,477 (270)

Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix

open access: yesFrontiers in Cellular Neuroscience, 2018
The neural extracellular matrix (ECM) is enriched with hyaluronic acid, chondroitin sulfate proteoglycans (CSPGs) and the glycoprotein tenascin-R, which play important roles in synaptic plasticity, as shown by studies of the CA1 region of the hippocampus.
Hussam Hayani   +4 more
doaj   +1 more source

Physiological sharp wave-ripples and interictal events in vitro: What’s the difference? [PDF]

open access: yes, 2014
Sharp wave-ripples and interictal events are physiological and pathological forms of transient high activity in the hippocampus with similar features.
Freund, Tamás   +7 more
core   +1 more source

Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses

open access: yeseLife, 2016
Mossy fiber synapses on CA3 pyramidal cells are 'conditional detonators' that reliably discharge postsynaptic targets. The 'conditional' nature implies that burst activity in dentate gyrus granule cells is required for detonation.
Nicholas P Vyleta   +2 more
doaj   +1 more source

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

open access: yesIranian Journal of Medical Sciences, 2016
Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown.
Chengdong Yuan   +6 more
doaj  

A compact aVLSI conductance-based silicon neuron [PDF]

open access: yesarXiv, 2015
We present an analogue Very Large Scale Integration (aVLSI) implementation that uses first-order lowpass filters to implement a conductance-based silicon neuron for high-speed neuromorphic systems. The aVLSI neuron consists of a soma (cell body) and a single synapse, which is capable of linearly summing both the excitatory and inhibitory postsynaptic ...
arxiv  

Random Walks for Spike-Timing Dependent Plasticity [PDF]

open access: yes, 2003
Random walk methods are used to calculate the moments of negative image equilibrium distributions in synaptic weight dynamics governed by spike-timing dependent plasticity (STDP). The neural architecture of the model is based on the electrosensory lateral line lobe (ELL) of mormyrid electric fish, which forms a negative image of the reafferent signal ...
arxiv   +1 more source

Genetically altered AMPA-type glutamate receptor kinetics in interneurons disrupt long-range synchrony of gamma oscillation [PDF]

open access: yes, 2001
Gamma oscillations synchronized between distant neuronal populations may be critical for binding together brain regions devoted to common processing tasks.
A. Bibbig   +51 more
core   +3 more sources

Connectivity reflects coding: A model of voltage-based spike-timing-dependent-plasticity with homeostasis [PDF]

open access: yes, 2009
Electrophysiological connectivity patterns in cortex often show a few strong connections in a sea of weak connections. In some brain areas a large fraction of strong connections are bidirectional, in others they are mainly unidirectional.
Claudia Clopath   +3 more
core   +1 more source

GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations [PDF]

open access: yes, 2003
Gamma (30–80 Hz) oscillations occur in mammalian electroencephalogram in a manner that indicates cognitive relevance. In vitro models of gamma oscillations demonstrate two forms of oscillation: one occurring transiently and driven by discrete afferent ...
A. Bibbig   +25 more
core   +2 more sources

Synaptic transmission mediated by single club endings on the goldfish Mauthner cell. II. Plasticity of excitatory postsynaptic potentials

open access: yesJournal of Neuroscience, 1988
Simultaneous pre- and postsynaptic intracellular recordings were used to analyze the properties of chemically mediated synaptic transmission between single club endings of eighth nerve afferents and the goldfish Mauthner (M-) cell lateral dendrite.
Jw Lin, D. Faber
semanticscholar   +1 more source

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