Results 101 to 110 of about 47,451 (277)

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Propofol enhances the field excitatory postsynaptic potentials in CA1 hippocampal slices of young and aged mice [PDF]

, 2014
Yiqing Yin, William J. Middleton, Carlos M. Florez, Peter L. Carlen, EI-Beheiry Hossam   +4 more
openalex   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Reduction of perineal evoked excitatory postsynaptic potentials in cat lumbar and sacral motoneurons during micturition [PDF]

, 1994
Brent Fedirchuk, Downie Jw, SJ Shefchyk
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Bidirectional Photoadaptive Organic Heterojunction Synaptic Transistors for Accurate Image Recognition in Machine Vision Systems

Advanced Science, EarlyView.
Bidirectional photoadaptive organic synaptic phototransistors are developed using complementary n–n and n‐p heterojunctions. These devices enable intelligent in‐sensor processing, markedly enhancing image contrast and edge features under adverse lighting, and achieve a recognition accuracy of 97.4% within ten training cycles for machine vision ...
Di Xue, Hongyu Liu, Yingying Zhang, Feng Ding, Jie Lu, Yao Yin, Zi Wang, Jianlong Xu, Lifeng Chi, Lizhen Huang   +9 more
wiley   +1 more source

ATP participates in three excitatory postsynaptic potentials in the submucous plexus of the guinea pig ileum

, 2004
R. L. Monro, Paul Bertrand, Joel C. Bornstein   +2 more
openalex   +1 more source

Compact Optical Reservoir Computing via Luminescence Dynamics in Rare‐Earth Ions‐Doped Nanocrystals

Advanced Science, EarlyView.
A functionally compact optical reservoir computing platform is demonstrated using rare‐earth ion‐doped nanocrystals, whose intrinsic nonlinear luminescence dynamics and multi‐timescale metastable states provide nonlinear mapping and fading memory without bulky delays or resonant structures.
Junyan Chen, Jingsong Fu, Jie Xu, Yixiang Qin, Axin Du, Kaiyang Wang, Limin Jin, Can Huang   +7 more
wiley   +1 more source

Network-wide modulation of synaptic plasticity and spike patterns in motor circuits after pallidal deep brain stimulation in a dystonia model

Neurobiology of Disease
Aims: We aimed to investigate the functional network effects of long-term deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) on synaptic activity in motor thalamic and motor cortical neurons in an animal model of generalised dystonia (
Denise Franz, Fabiana Santana Kragelund, Marco Heerdegen, Stefanie Perl, Anika Lüttig, Franz Veit Plocksties, Henning Bathel, Angelika Richter, Rüdiger Köhling   +8 more
doaj   +1 more source