Results 81 to 90 of about 5,216,810 (303)
Journal of High Energy Physics, 2021 We study the excited state Rényi entropy and subsystem Schatten distance in the two-dimensional free massless non-compact bosonic field theory, which is a conformal field theory.
Jiaju Zhang, M. A. Rajabpour
doaj +1 more source
Physics Letters B, 2001 AbstractThe 11B(7Li,7Be)11Be reaction at 57 MeV incident energy was studied at forward angles in order to explore the 11Be excitation energy spectrum. The 11Be ground state and the states at E∗=0.32,1.77,2.67,3.41,3.89,3.96,6.05 MeV excitation energies were populated. The state at 6.05 MeV (FWHM 320±40 keV) has not been previously observed.
Cappuzzello, F. +14 more
openaire +5 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Fromage: A Library for the Study of Molecular Crystal Excited States at the Aggregate Scale [PDF]
, 2019 The study of photoexcitations in molecular aggregates faces the twofold problem of the increased computational cost associated with excited states and the complexity of the interactions among the constituent monomers. A mechanistic investigation of these
Warda, Rahim +4 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Enhanced negative ion formation via electron attachment to electronically-excited states [PDF]
, 1995 Recent basic studies on electron attachment to laser-excited molecules show that electron attachment to electronically-excited states can have orders of magnitude larger cross sections compared to the respective ground electronic states.
Pinnaduwage, L.A.
core
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Ab initio study of ground and low excited states of NH radical
四川大学学报. 自然科学版, 2020 We study the ground state and low excited states of NH radical by using the CCSD(T) method in the coupled cluster theory and the secondary configuration interaction QCISD(T) method combined with the aug-cc- pv5z basis set.
LEI Liang-Jian +3 more
doaj
Interplay Between Locally Excited and Charge Transfer States Governs the Photoswitching Mechanism in Fluorescent Protein Dreiklang [PDF]
, 2020 We present the results of high-level electronic structure and dynamics simulationsof the photoactive protein Dreiklang. With the goal to understand the details ofDreiklang\u27s photocycle, we carefully characterize the excited states of the ON- andOFF ...
Yingying, Ma +5 more
core +2 more sources