Results 1 to 10 of about 370 (69)
Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu
Molecules, 2015 Macromolecular crowding is known to affect protein folding, binding of small molecules, interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein aggregation.
Irina M. Kuznetsova +4 more
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Hyaluronic Acid as Macromolecular Crowder in Equine Adipose-Derived Stem Cell Cultures
Cells, 2021 The use of macromolecular crowding in the development of extracellular matrix-rich cell-assembled tissue equivalents is continuously gaining pace in regenerative engineering.
Sergio Garnica-Galvez +6 more
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General Counteraction Exerted by Sugars against Denaturants
Life, 2021 The conformational stability of globular proteins is strongly influenced by the addition to water of different co-solutes. Some of the latter destabilize the native state, while others stabilize it.
Serena Cozzolino +3 more
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COMPUTER SIMULATION OF LOCAL MOBILITY IN DENDRIMERS WITH ASYMMETRIC BRANCHING BY BROWNIAN DYNAMICS METHOD [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2016 The Brownian dynamics method has been used to study the effect of the branching asymmetry on the local orientational mobility of segments and bonds in dendrimers in good solvent.
O. V. Shavykin +4 more
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Growth factor and macromolecular crowding supplementation in human tenocyte culture
Biomaterials and Biosystems, 2021 Cell-assembled tissue engineering strategies hold great potential in regenerative medicine, as three-dimensional tissue-like modules can be produced, even from a patient's own cells. However, the development of such implantable devices requires prolonged
Dimitrios Tsiapalis +3 more
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The unfolding of iRFP713 in a crowded milieu [PDF]
PeerJ, 2019 The exploring of biological processes in vitro under conditions of macromolecular crowding is a way to achieve an understanding of how these processes occur in vivo.
Olesya V. Stepanenko +3 more
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Allogeneic Serum and Macromolecular Crowding Maintain Native Equine Tenocyte Function in Culture
Cells, 2022 The absence of a native extracellular matrix and the use of xenogeneic sera are often associated with rapid tenocyte function losses during in vitro culture.
Andrea Rampin +6 more
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Life, 2022 Elastin-like polypeptides (ELPs) are soluble in water at low temperature, but, on increasing the temperature, they undergo a reversible and cooperative, coil-to-globule collapse transition.
Andrea Pica, Giuseppe Graziano
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On the Molecular Driving Force of Protein–Protein Association
Biophysica, 2022 The amount of water-accessible-surface-area, WASA, buried upon protein–protein association is a good measure of the non-covalent complex stability in water; however, the dependence of the binding Gibbs free energy change upon buried WASA proves to be not
Roberta Rapuano, Giuseppe Graziano
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Assembly of Microparticles to Patterned Trenches Using the Depletion Volume Effect
Micromachines, 2019 In this paper, we demonstrate that 20 μm microbeads can be preferentially assembled into substrate trenches of similar width by employing a polymer (depletant) that induces the depletion volume effect (depletion attraction).
Yaoki Mori, Ryota Kawai, Hiroaki Suzuki
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