Results 1 to 10 of about 54,592 (187)
Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu
Molecules, 2015 Macromolecular crowding is known to affect protein folding, binding of small molecules, interaction with nucleic acids, enzymatic activity, protein-protein interactions, and protein aggregation.
Irina M. Kuznetsova +4 more
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General Counteraction Exerted by Sugars against Denaturants
Life, 2021 The conformational stability of globular proteins is strongly influenced by the addition to water of different co-solutes. Some of the latter destabilize the native state, while others stabilize it.
Serena Cozzolino +3 more
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Life, 2022 Elastin-like polypeptides (ELPs) are soluble in water at low temperature, but, on increasing the temperature, they undergo a reversible and cooperative, coil-to-globule collapse transition.
Andrea Pica, Giuseppe Graziano
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On the Molecular Driving Force of Protein–Protein Association
Biophysica, 2022 The amount of water-accessible-surface-area, WASA, buried upon protein–protein association is a good measure of the non-covalent complex stability in water; however, the dependence of the binding Gibbs free energy change upon buried WASA proves to be not
Roberta Rapuano, Giuseppe Graziano
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Ion–ion correlation, solvent excluded volume and pH effects on physicochemical properties of spherical oxide nanoparticles [PDF]
Journal of Colloid and Interface Science, 2016 One major source of complexity in the implementation of nanoparticles in aqueous electrolytes arises from the strong influence that biological environments has on their physicochemical properties. A key parameter for understanding the molecular mechanisms governing the physicochemical properties of nanoparticles is the formation of the surface charge ...
Zaven Ovanesyan +6 more
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The unfolding of iRFP713 in a crowded milieu [PDF]
PeerJ, 2019 The exploring of biological processes in vitro under conditions of macromolecular crowding is a way to achieve an understanding of how these processes occur in vivo.
Olesya V. Stepanenko +3 more
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The Relevance of Cavity Creation for Several Phenomena Occurring in Water
Liquids, 2023 The solvent-excluded volume effect is an under-appreciated general phenomenon occurring in liquids and playing a fundamental role in many cases. It is quantified and characterized by means of the theoretical concept of cavity creation and its Gibbs free ...
Giuseppe Graziano
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Ionic asymmetry and solvent excluded volume effects on spherical electric double layers: A density functional approach [PDF]
The Journal of Chemical Physics, 2014 In this article, we present a classical density functional theory for electrical double layers of spherical macroions that extends the capabilities of conventional approaches by accounting for electrostatic ion correlations, size asymmetry, and excluded volume effects.
Bharat, Medasani +4 more
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Polymer Testing, 2023 So far, much less attention has been paid to the dynamic behavior of branched polymers under marginal solvent condition. This work reports the first study of the intrachain conformational relaxation of hyperbranched polystyrene (PS) chains under the ...
Xiaoyan Wang +3 more
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COMPUTER SIMULATION OF LOCAL MOBILITY IN DENDRIMERS WITH ASYMMETRIC BRANCHING BY BROWNIAN DYNAMICS METHOD [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2016 The Brownian dynamics method has been used to study the effect of the branching asymmetry on the local orientational mobility of segments and bonds in dendrimers in good solvent.
O. V. Shavykin +4 more
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