Results 11 to 20 of about 54,592 (187)
The effect of macromolecular crowding on the electrostatic component of barnase-barstar binding: a computational, implicit solvent-based study. [PDF]
PLoS ONE, 2014 Macromolecular crowding within the cell can impact both protein folding and binding. Earlier models of cellular crowding focused on the excluded volume, entropic effect of crowding agents, which generally favors compact protein states.
Helena W Qi +3 more
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Some Clues on the Conformational Stability of Globular Proteins
Trends in Peptide and Protein Sciences, 2019 The native structure of the glycine-rich antifreeze protein from snow flea, sfAFP, its conformational stability and cooperative folding-unfolding transitions represent a challenge for the current understanding and rationalization of protein folding and ...
Giuseppe Graziano
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The Scientific World Journal, 2014 It has recently been shown that aqueous solutions of tetrapropylammonium chloride and sulphate salts destabilize the folded conformation of Trp-peptides (Dempsey et al., 2011). This result is rationalized by the application of a statistical thermodynamic
Giuseppe Graziano
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Molecular-Scale Liquid Density Fluctuations and Cavity Thermodynamics
EntropyEquilibrium density fluctuations at the molecular level produce cavities in a liquid and can be analyzed to shed light on the statistics of the number of molecules occupying observation volumes of increasing radius.
Attila Tortorella, Giuseppe Graziano
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Energetics of cosolvent effect on peptide aggregation
Biophysics and Physicobiology, 2019 The cosolvent effect on the equilibrium of peptide aggregation is reviewed from the energetic perspective. It is shown that the excess chemical potential is stationary against the variation of the distribution function for the configuration of a flexible
Nobuyuki Matubayasi, Keiichi Masutani
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Ion size effect on colloidal forces within the primitive model
Condensed Matter Physics, 2005 The effect of ion size on the mean force between a pair of isolated charged particles in an electrolyte solution is investigated using Monte Carlo simulations within the framework of the primitive model where both colloidal particles and small ions are ...
J.Wu, S.Ravindran
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Acute Respiratory Distress Syndrome after Onyx Embolization of Arteriovenous Malformation
Critical Care Research and Practice, 2011 Purpose. We report a case of a 60-year-old male who underwent sequential Onyx embolizations of a cerebral arteriovenous malformation (AVM) which we implicate as the most likely etiology of subsequent acute respiratory distress syndrome (ARDS).
Isaac Tawil +2 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source