Results 21 to 30 of about 370 (69)

Melting Down Protein Stability: PAPS Synthase 2 in Patients and in a Cellular Environment

Frontiers in Molecular Biosciences, 2019
Within the crowded and complex environment of the cell, a protein experiences stabilizing excluded-volume effects and destabilizing quinary interactions with other proteins. Which of these prevail, needs to be determined on a case-by-case basis.
Oliver Brylski, Simon Ebbinghaus, Jonathan W. Mueller, Jonathan W. Mueller   +3 more
doaj   +1 more source

Chirally Improved Quark Pauli Blocking in Nuclear Matter and Applications to Quark Deconfinement in Neutron Stars

Particles, 2020
The relativistic mean field (RMF) model of the nuclear matter equation of state was modified by including the effect of Pauli-blocking owing to quark exchange between the baryons.
David Blaschke, Hovik Grigorian, Gerd Röpke   +2 more
doaj   +1 more source

Excluded volume effect of surfactant ligands on the shape of nascent nanocrystal

Condensed Matter Physics
We investigate the effect of the excluded volume of surfactant ligands on the shape of incipient quantum dots (QDs) to which they are attached. We consider a model in which ligands are represented by hard-sphere particles that are bound to the surface ...
Andrij Baumketner, Dmytro Anokhin, Yaropolk Patsahan   +2 more
doaj   +1 more source

Impact of electroviscous effect on viscosity in developing highly concentrated protein formulations: Lessons from non-protein charged colloids

International Journal of Pharmaceutics: X, 2019
Subcutaneous delivery of highly concentrated protein formulations is paramount for reducing healthcare cost and improving patient compliance, where reducing the solution viscosity of formulations is critical for drug delivery. The objective of this paper
Jinjiang Li, Yuan Cheng, Xiaodong Chen, Songyan Zheng   +3 more
doaj   +1 more source

Crowding alone cannot account for cosolute effect on amyloid aggregation.

PLoS ONE, 2011
Amyloid fiber formation is a specific form of protein aggregation, often resulting from the misfolding of native proteins. Aimed at modeling the crowded environment of the cell, recent experiments showed a reduction in fibrillation halftimes for amyloid ...
Shahar Sukenik, Regina Politi, Lior Ziserman, Dganit Danino, Assaf Friedler, Daniel Harries   +5 more
doaj   +1 more source

Anti-inflammatory activity of a natural herbal-marine drug (MS14 - SANT and SUSP) compared to sodium salicylate or methylprednisolone in a rat model for multiple sclerosis

European Journal of Translational Myology, 2021
A natural compound of marine herbal origin has been used in Persian Traditional Medicine to relieve some symptoms of multiple sclerosis. The present study investigated the anti-inflammatory effects of a patented extracts of the traditional receipt (MS14).
Mohsen Naseri, Hossein Rezaeizadeh, Mahdi Mirghazanfari, Taiebeh Taheripanah, Zahra Bararpoor, Neda Ashayeri, Majid Asghari, Abbas Talebi Mazrae Shahi, Fatemeh Emadi, Parvaneh Mohseni Moghaddam, Abbas Hashemi Nejad, Farzaneh Ghaffari   +11 more
doaj   +1 more source

Radial artery neointimal hyperplasia after transradial PCI-Serial optical coherence tomography volumetric study. [PDF]

PLoS ONE, 2017
Transradial catheterization (TRC) is a dominant access site for coronary catheterization and percutaneous coronary interventions (PCI) in many centers. Previous studies reported higher intimal thickness of the radial artery (RA) wall in patients with a ...
Petr Kala, Jan Kanovsky, Tereza Novakova, Roman Miklik, Otakar Bocek, Martin Poloczek, Petr Jerabek, Lenka Prymkova, Tomas Ondrus, Jiri Jarkovsky, Milan Blaha, Gary S Mintz   +11 more
doaj   +1 more source

Some Clues on the Conformational Stability of Globular Proteins

Trends in Peptide and Protein Sciences, 2019
The native structure of the glycine-rich antifreeze protein from snow flea, sfAFP, its conformational stability and cooperative folding-unfolding transitions represent a challenge for the current understanding and rationalization of protein folding and ...
Giuseppe Graziano
doaj   +1 more source

Investigation of cortical thickness and volume during spontaneous attacks of migraine without aura: a 3-Tesla MRI study

The Journal of Headache and Pain, 2021
Background Structural imaging has revealed changes in cortical thickness in migraine patients compared to healthy controls is reported, but presence of dynamic cortical and subcortical changes during migraine attack versus inter-ictal phase is unknown ...
Faisal Mohammad Amin, Roberto De Icco, Mohammad Al-Mahdi Al-Karagholi, Jayachandra M. Raghava, Frauke Wolfram, Henrik B. W. Larsson, Messoud Ashina   +6 more
doaj   +1 more source

Molecular-Scale Liquid Density Fluctuations and Cavity Thermodynamics

Entropy
Equilibrium density fluctuations at the molecular level produce cavities in a liquid and can be analyzed to shed light on the statistics of the number of molecules occupying observation volumes of increasing radius.
Attila Tortorella, Giuseppe Graziano
doaj   +1 more source