Results 151 to 160 of about 1,045,131 (310)
Cohesión social y exclusión. Una mirada desde Centroamérica [PDF]
, 2007 El concepto de cohesión social, emparentado con la definición sociológica\ud de integración social, señala problemas de relación entre\ud Estado y Sociedad cuya síntesis conduce a la respuesta de una sola\ud interrogante: ¿Son viables nuestras sociedades?
Sojo, Carlos
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Plazas de interacción social [PDF]
, 2015 Trabajo de gradoEl barrio los Olivos se ve condicionado por una serie de lineamientos que hacen de este un foco de problemática social, el cual limita su crecimiento y genera un lugar de exclusión dentro del sector.
Valbuena-Gutiérrez, Sandra Ximena
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Violencia, pobreza y exclusión social
Alternativas, 2002 Linares Márquez de Prado, Esperanza
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Exclusión social de los vecinos en una perspectiva comparada mundial
, 2019 Juan Díez-Nicolás +1 more
openalex +2 more sources