Results 111 to 120 of about 423,800 (304)
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Paul Winston Tetteh,1,4 Charles Antwi-Boasiako,1 Ben Gyan,3 Daniel Antwi,1 Festus Adzaku,1 Kwame Adu-Bonsaffoh,1,2 Samuel Obed21Department of Physiology, 2Department of Obstetrics and Gynecology, University of Ghana Medical School, Accra, Ghana ...
Adu-Bonsaffoh K +6 more
core
The efficiency of carbon conversion to biomass and desirable end products in industrial fermentations is diminished by the diversion of carbon to acetate and lactate excretions.
El-Mansi, Mansi
core +1 more source
Urinary cholesterol: its association with a macromolecular protein- lipid complex [PDF]
The cholesterol-containing complexes in the urine of normal subjects and patients with diseases accompanied by hyperexcretion of urinary cholesterol were characterized. In normal subjects, the major portion of the recovered urinary cholesterol was eluted
Jüngst, Dieter +3 more
core +1 more source
IntroductionCA102N is a novel anticancer drug developed by covalently linking H-Nim (N-(4-Amino-2-phenoxyphenyl methanesulfonamide) to Hyaluronic Acid to target CD44 receptor-rich tumors.
Eskouhie Tchaparian +7 more
doaj +1 more source
Phosphorus flux by macrobenthic invertebrates in a shallow eutrophic lake Donghu: spatial change
We estimated phosphorus flux mediated by benthic invertebrates from the sediments to the water in a shallow eutrophic lake (lake Donghu, central China) and quantified spatial (littoral and central sites) and specific (among different ...
Ji L. +7 more
doaj +1 more source
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
System Level Economic Analysis of Swine Diet Modifications [PDF]
Experimental data from low nitrogen and phosphorus diets (Carter et al, 1999, 2000, 2003) are being used to validate and/or modify the NRC swine growth model.
Stoecker, Arthur L., Lin, Yi-Hung
core
Knowledge of excretion rates of naturally occurring 210Po in non-exposed people is a prerequisite for assessment of potential internal contamination with polonium.
H. Straková, Z. Hölgye
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

