Results 121 to 130 of about 582,301 (339)
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
Studies on Urinary Excretion of Vitamin B12Co60 in Pernicious Anemia for Determining Effective Dosage of Intrinsic Factor Concentrates [PDF]
, 1956 William R. Best +4 more
openalex +1 more source
Most autophagic cell death studies lack evidence of causality
FEBS Open Bio, EarlyView.Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
FEBS Open Bio, EarlyView.This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
Estimated 24-Hour Urinary Sodium and Potassium Excretion in US Adults
Journal of the American Medical Association (JAMA), 2018 M. Cogswell +10 more
semanticscholar +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
MoleculesCompound 7–16 was designed and synthesized in our previous study and was identified as a more potential selective 5-HT2A receptor antagonist and inverse agonist for treating Parkinson’s disease psychosis (PDP).
Zhengping Hu +9 more
doaj +1 more source