Results 41 to 50 of about 337,234 (319)

Excretion and Residual Concentration Correlations of Salbutamol Between Edible Tissues and Living Samples in Pigs and Goats

Frontiers in Pharmacology, 2021
Illegal use of salbutamol (SAL), a β-adrenergic leanness-enhancing agent, has posed potential threat to human health in China. The excretion and depletion of SAL in pigs and goats were investigated, and the concentration correlations between edible ...
Lei Sun, Lei Sun, Lei Sun, Minjuan Zhu, Minjuan Zhu, Minjuan Zhu, Jingfei Shi, Jingfei Shi, Jingfei Shi, Kun Mi, Kun Mi, Wenjing Ma, Wenjing Ma, Wenjing Ma, Xiangyue Xu, Xiangyue Xu, Xiangyue Xu, Hanyu Wang, Hanyu Wang, Hanyu Wang, Yuanhu Pan, Yuanhu Pan, Yuanhu Pan, Yanfei Tao, Yanfei Tao, Yanfei Tao, Zhenli Liu, Zhenli Liu, Zhenli Liu, Lingli Huang, Lingli Huang, Lingli Huang   +31 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Quantum Behaviors on an Excreting Black Hole [PDF]

Class.Quant.Grav.26:125014,2009, 2008
Often, geometries with horizons offer insights into the intricate relationships between general relativity and quantum physics. However, some subtle aspects of gravitating quantum systems might be difficult to ascertain using static backgrounds, since quantum mechanics incorporates dynamic measurability constraints (such as the uncertainty principle ...
arxiv   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Rapidly Rotating, X-ray Bright Stars in the Kepler Field [PDF]

, 2016
We present Kepler light curves and optical spectroscopy of twenty X-ray bright stars located in the Kepler field of view. The stars, spectral type FK, show evidence for rapid rotation including chromospheric activity 100 times or more above the Sun at maximum and flaring behavior in their light curves.
arxiv   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Effects of hydrolysable tannin-treated grass silage on milk yield and composition, nitrogen partitioning and nitrogen isotopic discrimination in lactating dairy cows

Animal, 2020
The objective of this study was to evaluate the effects of oak tannin extract (OTE) added in forage before ensiling on dairy cows fed at 92% of their digestible protein requirements. Six multiparous lactating Holstein cows were used in a crossover design
S. Herremans, V. Decruyenaere, G. Cantalapiedra-Hijar, Y. Beckers, E. Froidmont   +4 more
doaj  

Vers une révision de la norme de production d'azote de la vache laitière : justification et conséquences sur le taux de liaison au sol des exploitations laitières [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2010
Towards a revison of the dairy cow’s standard for nitrogen production: justification and what are consequences for soil link rate of dairy farms. At present, the dairy cow’s standard of nitrogen production in Walloon region is 90 kg per year.
Lambert R., De Toffoli M., Dufrasne I., Hornick JL., Stilmant D., Seutin Y.   +5 more
doaj  

Anti-hyperuricemia effect of hesperetin is mediated by inhibiting the activity of xanthine oxidase and promoting excretion of uric acid

Frontiers in Pharmacology, 2023
Hesperetin is a natural flavonoid with many biological activities. In view of hyperuricemia treatment, the effects of hesperetin in vivo and in vitro, and the underlying mechanisms, were explored.
Meng-Fei An, Meng-Fei An, Chang Shen, Chang Shen, Shao-Shi Zhang, Shao-Shi Zhang, Ming-Yue Wang, Ming-Yue Wang, Ze-Rui Sun, Ze-Rui Sun, Mao-Si Fan, Mao-Si Fan, Li-Juan Zhang, Yun-Li Zhao, Yun-Li Zhao, Yun-Li Zhao, Jun Sheng, Jun Sheng, Jun Sheng, Xuan-Jun Wang, Xuan-Jun Wang, Xuan-Jun Wang   +21 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source