Results 21 to 30 of about 423,800 (304)

Predicting urinary creatinine excretion and its usefulness to identify incomplete 24h urine collections [PDF]

, 2012
Studies using 24 h urine collections need to incorporate ways to validate the completeness of the urine samples. Models to predict urinary creatinine excretion (UCE) have been developed for this purpose; however, information on their usefulness to ...
Dekkers, A.L.M., Rehurkova, I., Veer, P., van 't, de Boer, E., Keyzer, W., de, de Henauw, S., Crispim, S.P., de Keyzer, W., van 't Veer, P., Maele, G., van, Volatier, J.L., Slimani, N., Boer, E., de, Huybrechts, I., Ruprich, J., Hulshof, P.J.M., Andersen, L.F., van Maele, G., Geelen, A., Henauw, S., de   +19 more
core   +1 more source

Pre-Clinical Pharmacokinetic Characterization, Tissue Distribution, and Excretion Studies of Novel Edaravone Oral Prodrug, TEJ-1704

Pharmaceutics, 2021
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) is a free radical scavenger approved for the treatment of amyotrophic lateral sclerosis, a fatal neuromuscular disease. Edaravone is administered as an intravenous infusion over 60 min for several treatment
Dong Wook Kang, Ju Hee Kim, Kyung Min Kim, Seok-jin Cho, Hee-Woon Jang, Ji Won Chang, Seung Myung Dong, Jee Woong Lim, Jae-Sun Kim, Hea-Young Cho   +9 more
doaj   +1 more source

The Widely Conserved ebo Cluster Is Involved in Precursor Transport to the Periplasm during Scytonemin Synthesis in Nostoc punctiforme

mBio, 2018
Scytonemin is a dimeric indole-phenol sunscreen synthesized by some cyanobacteria under conditions of exposure to UVA radiation. While its biosynthetic pathway has been elucidated only partially, comparative genomics reveals that the scytonemin operon ...
Kevin Klicki, Daniela Ferreira, Demetra Hamill, Blake Dirks, Natalie Mitchell, Ferran Garcia-Pichel   +5 more
doaj   +1 more source

Intracellular Localization during Blood–Brain Barrier Crossing Influences Extracellular Release and Uptake of Fluorescent Nanoprobes

Nanomaterials, 2023
To improve the efficacy of nanoparticles (NPs) and boost their theragnostic potential for brain diseases, it is key to understand the mechanisms controlling blood–brain barrier (BBB) crossing.
Ornella Muscetti, Naym Blal, Valentina Mollo, Paolo Antonio Netti, Daniela Guarnieri   +4 more
doaj   +1 more source

Efficacy, Pharmacokinetics, Biodistribution and Excretion of a Novel Acylated Long-Acting Insulin Analogue INS061 in Rats

Drug Design, Development and Therapy, 2021
Kai Pan,1,2 Xiaolei Shi,2 Kai Liu,3 Ju Wang,2 Yijun Chen1 1State Key Laboratory of Natural Medicines and Laboratory of Chemical Biology, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, People’s Republic of China; 2Jiangsu Hengrui ...
Pan K, Shi X, Liu K, Wang J, Chen Y
doaj  

Biomarkers of isoflavone intake : validity at high intakes [PDF]

, 2007
Isoflavones are biologically active plant chemicals (phytoestrogens) which are ordinarily present in human diets. There is considerable research interest in their potential to prevent or treat several chronic diseases.
Mackinnon, L. Jay
core   +2 more sources

Sodium excretion and associated factors in urine samples of African descendants in Alcântara, Brazil: a population based study

Renal Failure, 2018
In most countries, salt intake has been excessive and constitutes one of the main risk factors for disease development, especially hypertension. Factors such as age, gender, sedentary lifestyle, smoking, African descent, obesity, dietary habits and ...
Elisângela Milhomem dos Santos, Dyego José de Araújo Brito, Isabela Leal Calado, Ana Karina Teixeira França, Joyce Santos Lages, Francisco das Chagas Monteiro Junior, Alcione Miranda dos Santos, Natalino Salgado Filho   +7 more
doaj   +1 more source

Excretion of Vancomycin-Resistant Enterococci by Wild Mammals

Emerging Infectious Diseases, 2002
A survey of fecal samples found enterococcal excretion in 82% of 388 bank voles (Clethrionomys glareolus), 92% of 131 woodmice (Apodemus sylvaticus), and 75% of 165 badgers (Meles meles). Vancomycin-resistant enterococci, all Enterococcus faecium of vanA
David J. P. Mallon, John E. Corkill, Sarah M. Hazel, J. Sian Wilson, Nigel P. French, Malcolm Bennett, C. Anthony Hart   +6 more
doaj   +1 more source

A novel member of the trehalose transporter family functions as an H+-dependent trehalose transporter in the reabsorption of trehalose in Malpighian tubules.

Frontiers in Physiology, 2012
In insects, Malpighian tubules are functionally analogous to mammalian kidneys in that they not only are essential to excrete waste molecules into the lumen but also are responsible for the reabsorption of indispensable molecules, such as sugars, from ...
Shingo eKikuta, Shingo eKikuta, Yuka eHagiwara-Komoda, Hiroaki eNoda, Hiroaki eNoda, Takahiro eKikawada   +5 more
doaj   +1 more source

Pharmacokinetics, Bioavailability, Excretion and Metabolism Studies of Akebia Saponin D in Rats: Causes of the Ultra-Low Oral Bioavailability and Metabolic Pathway

Frontiers in Pharmacology, 2021
Background: Akebia saponin D (ASD) has a variety of biological activities and great medicinal potential, but its oral bioavailability is so low as to limit its development.
Pengfei Li, Jun Peng, Yuexin Li, Lili Gong, Yali Lv, He Liu, Tianhong Zhang, Song Yang, Hongchuan Liu, Jinglai Li, Lihong Liu   +10 more
doaj   +1 more source