Results 61 to 70 of about 2,109,378 (288)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Кардиоваскулярная терапия и профилактика, 2005 Aim. To study the prevalence of arterial hypertension (AH) risk factors (RF), and their association, in Kemerovo City penitentiary system (KCPS) personnel. Material and methods.
A. V. Shabalin +5 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Death Row Confessions and the Last Meal Test of Innocence
Laws, 2013 Post hoc analyses of Rector v. Arkansas have regularly highlighted that the defendant requested that part of his last meal be saved so that he could it eat later.
Kevin M. Kniffin, Brian Wansink
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
LAWFUL BEHAVIOUR AS A SPECIAL TYPE OF THE PERSON’S SOCIAL BEHAVIOUR OF
Вестник Кемеровского государственного университета, 2014 The paper addresses the relation between social and lawful behavior of the person as a generic andspecific element, revealing their general and distinctive signs.
A. S. Morozov
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Adnan Menderes’i İdama Götüren Süreç ve İdamı
Journal of Universal History Studies, 2020 Adnan Menderes’in idamı ve bu idamın gerçekleşmesine yol açmış olan 27 Mayıs darbesi, Türkiye Cumhuriyeti tarihinde demokrasiye zarar veren önemli olaylardan birisi olmuştur.
Sabit Dokuyan, Büşra Yüksel
doaj +1 more source
Foundations and Trends® in Finance, 2015 The optimal design of executive compensation is one of the primary issues in the area of corporate governance and has been investigated in considerable detail in the academic literature over the past three decades. The underlying assumption behind the design of optimal compensation schemes is that the executives of the firm have more information on the
openaire +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source