Results 61 to 70 of about 937,369 (303)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Boutiques-execution-7ffb2e

open access: yes, 2019
Boutiques execution data ...
Anonymous, Anonymous (7293629)
core   +1 more source

An Anglo-Saxon execution cemetery at Walkington Wold, Yorkshire [PDF]

open access: yes, 2007
This paper presents a re-evaluation of a cemetery excavated over 30 years ago at Walkington Wold in east Yorkshire. The cemetery is characterized by careless burial on diverse alignments, and by the fact that most of the skeletons did not have ...
J.L. BUCKBERRY   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Deriving WCET Bounds by Abstract Execution

open access: yes, 2011
Standard static WCET analysis methods today are based on the IPET technique, where WCET estimation is formulated as an integer linear programming (ILP) problem subject to linear program flow constraints with an objective function derived from the ...
Ermedahl, Andreas,   +2 more
core   +7 more sources

LAWFUL BEHAVIOUR AS A SPECIAL TYPE OF THE PERSON’S SOCIAL BEHAVIOUR OF

open access: yesВестник Кемеровского государственного университета, 2014
The paper addresses the relation between social and lawful behavior of the person as a generic andspecific element, revealing their general and distinctive signs.
A. S. Morozov
doaj  

Death Row Confessions and the Last Meal Test of Innocence

open access: yesLaws, 2013
Post hoc analyses of Rector v. Arkansas have regularly highlighted that the defendant requested that part of his last meal be saved so that he could it eat later.
Kevin M. Kniffin, Brian Wansink
doaj   +1 more source

Distance: a New Metric for Controlling Granularity for Parallel Execution [PDF]

open access: yes, 1997
Granularity control is a method to improve parallel execution performance by limiting excessive parallelism. The general idea is that if the gain obtained by executing a task in parallel is less than the overheads required to support parallel execution ...
Santos Costa, Vitor   +8 more
core  

Boutiques-execution-4a9153

open access: yes, 2019
Boutiques execution data ...
Anonymous, Anonymous (7293629)
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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