Results 81 to 90 of about 2,109,378 (288)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Angiotensin receptor-1 antagonist eprosartan in patients with mild to moderate arterial hypertension
Кардиоваскулярная терапия и профилактика, 2005 Aim. To study clinical effectiveness of eprosartan mesylate in treating patients with Stage I-II arterial hypertension (AH). Material and methods. In total, 28 patients (20 males, 8 females) with Stage I-II AH, risk 2-3, aged 28-56 years (mean age 40.0±1.
A. V. Shabalin +2 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Vision-based deep execution monitoring
, 2017 Execution monitor of high-level robot actions can be effectively improved by visual monitoring the state of the world in terms of preconditions and postconditions that hold before and after the execution of an action.
Grazioso, Simone +5 more
core
Chiminey: Reliable Computing and Data Management Platform in the Cloud
, 2015 The enabling of scientific experiments that are embarrassingly parallel, long running and data-intensive into a cloud-based execution environment is a desirable, though complex undertaking for many researchers. The management of such virtual environments
Androulakis, Steve +9 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A Visual Stack Based Paradigm for Visualization Environments [PDF]
, 2005 We present a new visual paradigm for Visualization Systems, inspired by stack-based programming. Most current implementations of Visualization systems are based on directional graphs.
Gilbert, Matt, Lombeyda, Santiago
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2018 The article presents a substantial analysis of the Federal state educational standards (undergraduate and graduate level), implemented in the educational process of educational organizations subordinated to the Federal penitentiary service, in order to ...
Anna L. Morozova
doaj