Results 71 to 80 of about 937,369 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The speed of limit order execution in the Spanish stock exchange [PDF]

open access: yes, 2005
The objective of this work is to study empirically the factors influencing the execution time in the Spanish Stock Exchange. Our dataset includes the orders and transactions of the assets belonging to IBEX 35 in the period between July and September 2000.
Gava, Luana
core   +1 more source

Psychosomatic status parameters and cardiovascular remodeling in patients with arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2005
The review is devoted to the role of psychosomatic status factors in the development of pathological cardiovascular remodeling in essential arterial hypertension.
A. V. Shabalin   +4 more
doaj  

Adaptive workflow processing and execution in Pegasus [PDF]

open access: yes, 2008
Workflows are widely used in applications that require coordinated use of computational resources. Workflow definition languages typically abstract over some aspects of the way in which a workflow is to be executed, such as the level of parallelism to be
Kevin Lee   +17 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Adnan Menderes’i İdama Götüren Süreç ve İdamı

open access: yesJournal of Universal History Studies, 2020
Adnan Menderes’in idamı ve bu idamın gerçekleşmesine yol açmış olan 27 Mayıs darbesi, Türkiye Cumhuriyeti tarihinde demokrasiye zarar veren önemli olaylardan birisi olmuştur.
Sabit Dokuyan, Büşra Yüksel
doaj   +1 more source

About Parallel Programming: Paradigms, Parallel Execution and Collaborative Systems [PDF]

open access: yes
In the last years, there were made efforts for delineation of a stabile and unitary frame, where the problems of logical parallel processing must find solutions at least at the level of imperative languages.
Monica CIACA, Loredana MOCEAN
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Execution Risk [PDF]

open access: yes
Transaction costs in trading involve both risk and return. The return is associated with the cost of immediate execution and the risk is a result of price movements during a more gradual trading. The paper shows that the trade-off between risk and return
Robert Engle, Robert Ferstenberg
core  

Home - About - Disclaimer - Privacy