Results 61 to 70 of about 11,920,917 (378)

Altered Executive Function in Suicide Attempts

European Psychiatry, 2022
Introduction Executive function organizes and directs behaviour but alterations in this cognitive domain can lead to inaccurate perception, interpretation and response to environmental information, which could be a risk factor for suicide.
J. Fernández, S. Alberich, I. Zorrilla, I. González-Ortega, M.P. López, V. Pérez-Solà, E. Vieta, A.M. González-Pinto, P.A. Saiz   +8 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Executive Function, Eating Behavior, and Preoperative Weight Loss in Bariatric Surgery Candidates: An Observational Study

Obesity Facts, 2019
Background: Individual differences in executive function may influence eating behavior, weight loss (WL), and WL maintenance in obesity treatment. Executive function, which designates top-down cognitive control processes, has been related to eating ...
Gro Walø-Syversen, Ingela L. Kvalem, Jon Kristinsson, Inger L. Eribe, Øyvind Rø, Camilla Lindvall Dahlgren   +5 more
doaj   +1 more source

Executive function in first-episode schizophrenia [PDF]

, 1998
BACKGROUND: We tested the hypothesis that schizophrenia is primarily a frontostriatal disorder by examining executive function in first-episode patients.
Barnes, T R, Duncan, L J, Hutton, Samuel, Joyce, E m, Puri, B K, Robbins, T w   +5 more
core   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Effects of a multicomponent exercise on dual-task performance and executive function among older adults

International Journal of Gerontology, 2018
Summary: Background: Previous studies showed that multicomponent exercise enhanced physical and cognitive functions. This study aimed to investigate the effects of a multicomponent exercise on dual-task performance and executive function and to ...
Ray-Yau Wang, Yuan-Li Wang, Fang-Yu Cheng, Yuan-Hung Chao, Chien-Liang Chen, Yea-Ru Yang   +5 more
doaj   +1 more source

The Correlation Between Thyroid Function, Frontal Gray Matter, and Executive Function in Patients With Major Depressive Disorder

Frontiers in Endocrinology, 2021
The present study was aimed to investigate the relationships between serum thyroid hormones (THs), frontal gray matter volume, and executive function in selected patients with major depressive disorder (MDD). One hundred and four MDD patients and seventy-
Shuai Zhao, Yi Xia, Yinghong Huang, Haowen Zou, Xumiao Wang, Zhilu Chen, Hongliang Zhou, Yinglin Han, Hao Tang, Rui Yan, Zhijian Yao, Zhijian Yao, Qing Lu, Qing Lu   +13 more
doaj   +1 more source

Dietary Patterns and Cognitive Function among Older Community-Dwelling Adults. [PDF]

, 2018
Diet may be an important modifiable risk factor for maintenance of cognitive health in later life. This study aimed at examining associations between common dietary indices and dietary patterns defined by factor analysis and cognitive function in older ...
Barrett-Connor, Elizabeth, Kritz-Silverstein, Donna, Laughlin, Gail A, McEvoy, Linda K, Reas, Emilie T, Richard, Erin L   +5 more
core   +3 more sources

Associations Among Body Mass Index, Cortical Thickness, and Executive Function in Children.

JAMA pediatrics, 2019
Importance A total of 25.7 million children in the United States are classified as overweight or obese. Obesity is associated with deficits in executive function, which may contribute to poor dietary decision-making.
J. Laurent, R. Watts, S. Adise, N. Allgaier, B. Chaarani, H. Garavan, A. Potter, S. Mackey   +7 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source