Results 81 to 90 of about 11,920,917 (378)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Executive function during typing on computer

open access: yesСовременная зарубежная психология, 2022
In recent decades, computer typing has become one of the fundamental tools for personal communication in everyday life. Typing is a multi-level hierarchical process that involves a large number of cognitive and physiological functions ...
D.A. Momotenko
doaj   +1 more source

Longitudinal evaluation of cognitive functioning in young children with type 1 diabetes over 18 months [PDF]

open access: yes, 2016
OBJECTIVE: Decrements in cognitive function may already be evident in young children with type 1 diabetes (T1D). Here we report prospectively acquired cognitive results over 18 months in a large cohort of young children with and without T1D. METHODS: 144
Ambrosino, Jodie   +12 more
core   +2 more sources

Childhood socioeconomic status and executive function in childhood and beyond

open access: yesPLoS ONE, 2018
Socioeconomic status (SES) predicts health, wellbeing, and cognitive ability, including executive function (EF). A body of recent work has shown that childhood SES is positively related to EF, but it is not known whether this disparity grows, diminishes ...
Briana S. Last   +4 more
semanticscholar   +1 more source

Imaging the genetics of executive function [PDF]

open access: yesBiological Psychology, 2008
Recent advances in neuroimaging technologies have allowed ever more detailed studies of the human brain. The combination of neuroimaging techniques with genetics may provide a more sensitive measure of the influence of genetic variants on cognitive function than behavioural measures alone.
Greene, C. M.   +3 more
openaire   +6 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT) [PDF]

open access: yes, 2011
Rationale: Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and
A Costa   +52 more
core   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

open access: yesFEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh   +2 more
wiley   +1 more source

Speech-in-speech perception and executive function involvement. [PDF]

open access: yesPLoS ONE, 2017
This present study investigated the link between speech-in-speech perception capacities and four executive function components: response suppression, inhibitory control, switching and working memory. We constructed a cross-modal semantic priming paradigm
Marcela Perrone-Bertolotti   +2 more
doaj   +1 more source

ERP evidence suggests executive dysfunction in ecstasy polydrug users [PDF]

open access: yes, 2013
Background: Deficits in executive functions such as access to semantic/long-term memory have been shown in ecstasy users in previous research. Equally, there have been many reports of equivocal findings in this area.
A Gamma   +53 more
core   +1 more source

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