Results 51 to 60 of about 11,535,511 (379)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Self-reported nutritional status, executive functions, and cognitive flexibility in adults [PDF]

, 2018
Objectives. The purpose of this study was to investigate the relationship between nutrition status, executive cognitive functions, and cognitive flexibility; and to analyze the role of gender, age, and nutrition status in the prediction of executive ...
Khodarahimi, Siamak
core   +1 more source

The executive

, 2012
With the election of Leung Chun-ying as the fourth chief executive (CE) of the Hong Kong Special Admininstration Region (HKSAR), the people of Hong Kong are keen to have a new government with policy visions and leadership.
LI, Pang Kwong
core   +2 more sources

Early childhood teachers’ understanding of executive functions and strategies employed to facilitate them

Frontiers in Education
IntroductionAdult-child interactions have a noteworthy influence over how executive functions develop. However, despite recognising the importance of executive functions in a child’s success, little research has been undertaken to explore the role of ...
Parian Madanipour, Susanne Garvis, Caroline Cohrssen, Donna Pendergast   +3 more
doaj   +1 more source

Perception of Caregiving During Childhood is Related to Later Executive Functions and Antisocial Behavior in At-Risk Boys

Frontiers in Psychiatry, 2020
Executive functions are considered essential for effective navigation in the social world. Parental responsiveness is a critical ingredient for normative social development and, as such, may be connected with the development of executive functions ...
Anna Harwood-Gross, Bar Lambez, Ruth Feldman, Yuri Rassovsky, Yuri Rassovsky, Yuri Rassovsky   +5 more
doaj   +1 more source

Executive Functions and Foreign Language Learning

Pediatric Reports, 2022
Executive functions (EFs) serve as an umbrella term to describe a set of higher-order cognitive abilities that include working memory, inhibitory control, cognitive flexibility, planning, reasoning, and problem-solving.
Alessandro Frolli, Francesco Cerciello, Clara Esposito, Sonia Ciotola, Gaia De Candia, Maria Carla Ricci, Maria Grazia Russo   +6 more
doaj   +1 more source

The relationships between rumination and core executive functions: A meta‐analysis

Depression and Anxiety, 2017
Rumination has been thought to relate to deficits in core executive functions (EFs), but the empirical findings for this idea are mixed. The aim of the present study is to synthesize existing literature to clarify these relations.
Yingkai Yang, Songfeng Cao, G. Shields, Zhaojun Teng, Yanling Liu   +4 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Is intelligence equivalent to executive functions?

Psicothema, 2018
BACKGROUND Since the mid 19th century, cognitive and behavioral neurosciences have attempted to find the neurological bases of intellectual abilities. During the early 20th century the psychometric concept of "intelligence" was coined; and toward the end
A. Ardila
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source