Results 71 to 80 of about 1,080,536 (302)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Incidence of Executive Functions on Reading Comprehension Performance in Adolescents [PDF]

open access: yes, 2014
Introducción.La comprensión lectora es una habilidad cognitiva compleja que se ha asocia-do a procesos ejecutivoscomola memoria de trabajo (MT) y la inhibición.
Canet Juric, Lorena   +2 more
core  

Cultural variation in cognitive flexibility reveals diversity in the development of executive functions [PDF]

open access: yes, 2018
Cognitive flexibility, the adaptation of representations and responses to new task demands, improves dramatically in early childhood. It is unclear, however, whether flexibility is a coherent, unitary cognitive trait, or is an emergent dimension of task ...
Dale, Michael   +3 more
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The typical developmental trajectory of social and executive functions in late adolescence and early adulthood. [PDF]

open access: yes, 2012
Executive functions and social cognition develop through childhood into adolescence/early adulthood and are important for adaptive goal-oriented behaviour (Apperly, Samson & Humphreys, 2009; Blakemore & Choudhury, 2006). These functions are attributed to
Barker, Lynne   +3 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Anomalies in the cognitive-executive functions in patients with chiari malformation type I [PDF]

open access: yes, 2018
Resumen tomado de la publicaciónAnomalías en las funciones cognitivo-ejecutivas en pacientes con la Malformación de Chiari Tipo I. Antecedentes: en la última década, existen evidencias crecientes de que déficits neuropsicológicos, esencialmente en ...
Besteiro González, José Luis   +1 more
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Consent for further education colleges to invest in companies [PDF]

open access: yes, 2011
Summary: This guidance document is aimed at college principals and finance directors as well as staff within the Skills Funding Agency. It lays out the requirements for Further Education (FE) colleges to seek Skills Funding Agency (the Agency) consent to

core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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