Results 71 to 80 of about 3,370,533 (301)

Executive Functions as a Predictor of the Teacher’s Didactic Competencies

Educational Process: International Journal
Background/purpose. Executive functions are generally considered crucial for an individual's capacity to adapt. This also applies to the domain of professional competencies.
Viktor Gatial , Andrea Šášiková
doaj   +1 more source

Executive Functions in the Mental Set Formation Process: Shifting, Updating, Inhibition

Экспериментальная психология
This study examined the mechanisms of mental set (Einstellung effect) formation. Earlier it was shown that executive functions are a system-forming element in the structure of the formation mental set mechanisms. Executive functions (shifting,
N.Yu. Lazareva, A.V. Chistopolskaya, I.Y. Vladimirov   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Salivary Cortisol Mediates Effects of Poverty and Parenting on Executive Functions in Early Childhood [PDF]

In a predominantly low-income population-based longitudinal sample of 1,292 children followed from birth, higher level of salivary cortisol assessed at ages 7, 15, and 24 months was uniquely associated with lower executive function ability and to a ...
Douglas A. Granger, FLP Investigators, Christine K. Fortunato, Clancy Blair, Michael Willoughby, Martha Cox, Mark T. Greenberg, Roger Mills-Koonce, Katie T. Kivlighan   +8 more
core  

Executive functions in insight versus non-insight problem solving: An individual differences approach [PDF]

, 2009
This is the author's accepted manuscript (with the working title "Executive processes and working memory in solving insight and non-insight problems"). The final published article is available from the link below.
Gilhooly, KJ, Gilhooly, K. J., Gilhooly, K., Fioratou, E, Fioratou, E.   +4 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The effectiveness of training of hot and cool executive functions at both parent and child levels on executive functions in children with attention deficit hyperactivity disorder (ADHD)

مجله علوم روانشناختی, 2022
Background: Most children with ADHD have impairments in both the cool (cognitive) and hot (emotional, motivational) aspects of executive functions; however, the interventions focused more on the cool aspect of these actions. Aims: The present study aimed
Seyyedeh Zahra Seyyed Noori, AbbasAli Hosseinkhanzadeh, Abbas Abolghasemi, Iraj Shakerinia   +3 more
doaj  

Executive and Intellectual Functions in ADHD

Pediatric Neurology Briefs, 2011
The relationship between executive functions (EF), ADHD subtypes, and comorbid diagnoses, and the potential role of IQ were investigated in the Child Neuropsychiatry Unit, Children's Hospital, Rome, Italy.
J Gordon Millichap
doaj   +1 more source