Results 51 to 60 of about 1,080,536 (302)

ERP evidence suggests executive dysfunction in ecstasy polydrug users [PDF]

open access: yes, 2013
Background: Deficits in executive functions such as access to semantic/long-term memory have been shown in ecstasy users in previous research. Equally, there have been many reports of equivocal findings in this area.
A Gamma   +53 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Threat-Modulation of Executive Functions—A Novel Biomarker of Depression?

open access: yesFrontiers in Psychiatry, 2021
Background: Alterations in executive functions, emotion regulation, and their interaction are common concomitants of depression. Executive dysfunction frequently lingers after treatment, has adverse effects on daily life, and predisposes to recurrence of
Jari Peräkylä   +8 more
doaj   +1 more source

Conditioning U.S. Security Assistance on Human Rights Practices [PDF]

open access: yes, 1982
In the United States, with its government of separated powers and functions, it is the executive branch, and in particular the Department of State, that bears responsibility for implementing legislation on foreign relations. The success of implementation
Cohen, Stephen B.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Working Memory in Writing: Empirical Evidence From the Dual-Task Technique [PDF]

open access: yes, 2003
The dual-task paradigm recently played a major role in understanding the role of working memory in writing. By reviewing recent findings in this field of research, this article highlights how the use of the dual-task technique allowed studying ...
Olive, Thierry
core   +4 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Effects of executive functions on consecutive interpreting for Chinese-Japanese unbalanced bilinguals

open access: yesFrontiers in Psychology, 2023
IntroductionPrevious research on performance in interpreting has focused primarily on the influence of interpreting experience on executive functions, such as shifting, updating, and inhibition.
Qichao Song, Ting Song, Xiaodong Fei
doaj   +1 more source

Shifting gear in the study of the bilingual advantage : language switching examined as a possible moderator [PDF]

open access: yes, 2019
The bilingual advantage is a heavily debated topic in research on bilingualism. The current study further investigated one specific aspect of bilingualism proposed to be a determining factor for the bilingual advantage, namely language switching ...
Struys, Esli   +2 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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