Results 181 to 190 of about 5,770,745 (393)

Exercise capacity and mortality among men referred for exercise testing.

open access: yesNew England Journal of Medicine, 2002
J. Myers   +5 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Effects of exercise training on cardiac output in subjects with heart failure with preserved ejection fraction (HFpEF) — a protocol for a systematic review and meta-analysis

open access: yesSystematic Reviews
Background Patients with heart failure with preserved ejection fraction (HFpEF) commonly experience exercise intolerance, resulting in reduced cardiorespiratory fitness.
Raphael Schoch   +4 more
doaj   +1 more source

Effect of Forced Exercise on Bull Fertility

open access: bronze, 1955
Jesse Snyder, N.P. Ralston
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

EXERCISE TOLERANCE IN HEART DISEASE [PDF]

open access: green, 1922
Theodore B. Barringer
openalex   +1 more source

American College of Sports Medicine position stand. Exercise and physical activity for older adults.

open access: yesMedicine & Science in Sports & Exercise, 2009
W. Chodzko-Zajko   +6 more
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

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