Results 91 to 100 of about 7,733,951 (272)

The trainability of movement quality and its role in guiding exercise prescription and influencing physical performance /

open access: yes, 2019
1 ethesis (xx, 402 pages) :illustrations.Includes bibliographical references (pages 386-402)Movement assessments have been used in practice to identify injury risk and performance capabilities, albeit with little success.
Bennett, Hunter
core  

The Effects of Physical Exercise on Pain Management in Patients with Knee Osteoarthritis: A Systematic Review with Metanalysis [PDF]

open access: yesRevista Brasileira de Ortopedia
Objective The present study verified, through a systematic review with meta-analysis, the effects of a rehabilitation, physical training program for the treatment of pain and muscle strength in knee osteoarthritis (OA).
Thiago Casali Rocha   +3 more
doaj   +4 more sources

Comparing the Effects of Manual and Self-exercise Therapy for Improving Forward Head Posture

open access: yesPhysical Therapy Korea, 2023
Background: Studies investigating the immediate effects of a single intervention to correct forward head posture are rare. Objects: This study aimed to compare the changes in treatment effects in patients with forward head posture and neck pain after ...
Gyeongseop Sim   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Physical Activity Level and Exercise Barriers According to the Transtheoretical Model in Breast Cancer Patients

open access: yes, 2022
PURPOSE: The purpose of this study is to investigate the physical activity (PA) and exercise barriers of stages 0-3 breast cancer survivors according to the Transtheoretical Model (TTM). METHODS: This cross-sectional study that included data from a total
박형석, 김승일, 김지예
core   +1 more source

How to prescribe physical exercise in rheumatology

open access: yesReumatismo, 2011
Physical exercise, aiming to improve range of movement, muscle strength and physical well being, lately substituted the immobilization previously prescribed in rheumatic diseases.
S. Maddali Bongi, A. Del Rosso
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Minutes of the New Unity Movement, South Peninsula Branch, meeting held on 27 September 2009

open access: yes, 2009
Minutes of the New Unity Movement, South Peninsula Branch, meeting held on Sunday, 27 September ...
New Unity Movement
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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