Results 101 to 110 of about 670,076 (282)
Introduction: Stereotypy is one of the main features of children with autism. These behaviors are associated with deficit in learning processes, social skills acquisition, increased family stress, and self-injuries behaviors.
Fatimah Bahrami +4 more
doaj +1 more source
Pain management for chronic musculoskeletal conditions : the development of an evidence-based and theory-informed pain self-management course [PDF]
Objective: To devise and test a self-management course for chronic pain patients based on evidence and underpinned by theory using the Medical Research Council (MRC) framework for developing complex interventions.
Carnes, Dawn +5 more
core +3 more sources
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
The Pairing of Trigger Point Dry Needling with Rehabilitation Techniques [PDF]
Trigger point dry needling is a manual treatment modality used for individuals experiencing tightness, pain, and inhibited range of motion in any region of the body.
Kotze, Karle
core +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Training for muscular power adaptations : the role of contraction type and velocity [PDF]
Muscular power, an integral component in most sport, is the product of force and velocity. Power is often viewed as synonymous, yet incorrectly, with strength. Where power has an inherent speed component, strength is independent of movement velocity, and
Brenneman, Michael Travis
core +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Exercise provides significant benefits for physical health, and weightlifting has become increasingly popular among fitness enthusiasts. However, improper lifting techniques often lead to injuries, discouraging beginners and affecting long-term training ...
Nicholas Dylan Lienardi, Evan Tanuwijaya
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

