Results 101 to 110 of about 670,076 (282)

The effect of training two selected karate-hand techniques on hand stereotypic movements in autistic boy (Case study)

open access: yesمجله پژوهش در علوم توانبخشی, 2013
Introduction: Stereotypy is one of the main features of children with autism. These behaviors are associated with deficit in learning processes, social skills acquisition, increased family stress, and self-injuries behaviors.
Fatimah Bahrami   +4 more
doaj   +1 more source

Pain management for chronic musculoskeletal conditions : the development of an evidence-based and theory-informed pain self-management course [PDF]

open access: yes, 2013
Objective: To devise and test a self-management course for chronic pain patients based on evidence and underpinned by theory using the Medical Research Council (MRC) framework for developing complex interventions.
Carnes, Dawn   +5 more
core   +3 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

The Pairing of Trigger Point Dry Needling with Rehabilitation Techniques [PDF]

open access: yes, 2019
Trigger point dry needling is a manual treatment modality used for individuals experiencing tightness, pain, and inhibited range of motion in any region of the body.
Kotze, Karle
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Training for muscular power adaptations : the role of contraction type and velocity [PDF]

open access: yes, 2016
Muscular power, an integral component in most sport, is the product of force and velocity. Power is often viewed as synonymous, yet incorrectly, with strength. Where power has an inherent speed component, strength is independent of movement velocity, and
Brenneman, Michael Travis
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Application of YOLO11 and Long Short-Term Memory Architecture for Exercise Form Evaluation in Weightlifting

open access: yesJurnal Teknologi dan Manajemen Informatika
Exercise provides significant benefits for physical health, and weightlifting has become increasingly popular among fitness enthusiasts. However, improper lifting techniques often lead to injuries, discouraging beginners and affecting long-term training ...
Nicholas Dylan Lienardi, Evan Tanuwijaya
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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