Results 231 to 240 of about 3,646,791 (298)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

A Co-clinical Trial of Exercise Therapy in Breast Cancer Prevention. [PDF]

Clin Cancer Res
Jones LW, Lavery JA, Tsai BL, Moskowitz CS, Lee CP, Harrison J, Michalski MG, Stoeckel K, Graham C, Iyengar NM, Bhanot U, Linkov I, Jain M, Jochelson MS, Monetti M, Seewaldt VL, Pilewskie ML, Pribil P, Zhu C, Arbet J, Mangino DA, Boutros PC.   +21 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Efficacy of exercise therapy in adolescent idiopathic scoliosis: A meta-analysis. [PDF]

J Int Med Res
Ma Z, Wang S, Zhang S.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Development of an Iranian Clinical Guideline on Perioperative Exercise Therapy for Metabolic and Bariatric Surgery: A Delphi Consensus Study Using the AGREE II Framework. [PDF]

Int J Endocrinol Metab
Nejati P, Kabir A, Mazaherinezhad A, Dadgostar H, Kermansaravi M, Nejati L.   +5 more
europepmc   +1 more source

A systematic review and meta-analysis of the efficacy of exercise therapy for the rehabilitation of rotator cuff-related shoulder pain: a subgroup analysis of racquet sport athletes. [PDF]

Front Bioeng Biotechnol
Wu J, Zheng Y, Cai W, Takeshita D, Loh PY, Hu G, He Y.   +6 more
europepmc   +1 more source

Exercise therapy for the treatment of delirium in the intensive care unit. [PDF]

Cochrane Database Syst Rev
Garegnani L, Ivaldi D, Burgos MA, Varela LB, Díaz Menai S, Rico S, Giménez ML, Escobar Liquitay CM, Franco JV.   +8 more
europepmc   +1 more source

Qualitative Assessment of Network Meta-Analyses of Exercise Therapy for Parkinson's Disease: A Scoping Review. [PDF]

Cureus
Ura S, Ota K, Kai T, Sugano K, Narita M, Kitagawa T.   +5 more
europepmc   +1 more source