Results 201 to 210 of about 12,556,675 (343)

Canine Urothelial DNA Mutations Are Not Associated With Total Trihalomethanes Concentrations in Municipal Drinking Water

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Contaminants in municipal drinking water, specifically total trihalomethanes (TTHMs), are mutagenic. Exposures to TTHMs have been associated with urothelial carcinoma (UC) in both people and dogs. Mutations in the BRAF gene and other genomic copy number aberrations detected in voided urothelial cells with commercial CADET BRAF and BRAF‐PLUS ...
Janice O'Brien   +6 more
wiley   +1 more source

Regional changes in cerebral blood flow between the upright and supine posture and over 3 days of bed rest

open access: yesExperimental Physiology, EarlyView.
Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig   +8 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Respiratory and non‐respiratory airflow characteristics across ingestive and non‐ingestive swallowing tasks

open access: yesExperimental Physiology, EarlyView.
Abstract Respiratory–swallowing coordination is critical for safe swallowing. Respiratory phase patterns, indicating the direction of respiration bracketing swallowing, appear minimally altered when oral airflow is measured alongside nasal airflow. Measures from an oronasal facemask also demonstrate broader features of swallowing non‐respiratory flow ...
Elizabeth Cross   +2 more
wiley   +1 more source

No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals

open access: yesExperimental Physiology, EarlyView.
Abstract Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure that are mirrored by middle cerebral artery blood velocity (MCAv). However, whether lower‐ or upper‐body RE elicits a differential cerebrovascular response has not yet been examined.
Stephanie Korad   +2 more
wiley   +1 more source

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