Results 121 to 130 of about 118,549 (282)

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Nasal Epithelial Immune Signatures Are Associated With Age‐Dependent Asthma Trajectories in Early Life

Allergy, EarlyView.
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth, Sabina Illi, Helen Charles, Madlen Oelsner, Amr A. Gabr, Ulrich M. Zissler, Anna Erb, Martin Feuerherd, Felix Drost, Maren Büttner, Benjamin Schubert, Nicole Maison, Jimmy Omony, Markus Weckmann, Ruth Grychtol, Anna‐Maria Dittrich, Svenja Foth, Chrysanthi Skevaki, Tobias Trojan, Silke van Koningsbruggen‐Rietschel, Gesine Hansen, Thomas Bahmer, Klaus F. Rabe, Folke Brinkmann, Matthias Volkmar Kopp, Ulrike Protzer, Adam M. Chaker, Bianca Schaub, Erika von Mutius, Carsten B. Schmidt‐Weber, the ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Mira Bürk, Sybille Contento, Markus Ege, Kristina Gottschau, Silvia Gschwendtner, Alexander Hose, Lena Lagally, Michael Schloter, Lena Ullemeyer, Esther Zeitlmann, Mustafa Abdo, Heike Biller, Karoline I. Gaede, Clara Haug, Nikolas Jacobs, Anne‐Marie Kirsten, Inke R. König, Lea Kronziel, Gyde Nissen, Frauke Pedersen, Loana Pennerd, Isabell Ricklefs, Vera Veith, Henrik Watz, Marie Bickes, Mifflin‐Rae Calvero, David S. DeLuca, Svenja Gaedcke, Anika Habener, Christine Happle, Adan Chari Jirmo, Bin Liu, Lennart Riemann, Nicolaus Schwerk, Inga Jerrentrup, Harald Renz, Stefanie Weber, Miguel A. Alejandre Alcazar, Samira Blau, Ernst Rietschel, Jan‐Christoph Thomassen   +71 more
wiley   +1 more source

Factors for Success and Failure of Allergen Immunotherapy (AIT) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergy, EarlyView.
ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk, Vera Mahler, Melanie Albrecht, Danilo di Bona, Benjamin Hofner, Jasper Kappen, Susanne Kaul, Graham Roberts, Mohamed H. Shamji, Stefan Vieths, Oliver Pfaar   +10 more
wiley   +1 more source

Breathing in Plants and Chaos—Cosmic Tree Events in Cameroon and Beyond

Anthropology of Consciousness, EarlyView.
ABSTRACT Contemporary practices of tapping into the wisdom of ancestral trees are described through three entangled recent events lived within the context of Bantu practices in Cameroon. In the three instances, the steered or chance encounters with high potency trees were serendipitous telling moments which brought something new to the horizon.
Julie Laplante, Armel Lekeufack, Nina Tamara Barbosa Ponce, Roger Amos Kañaa   +3 more
wiley   +1 more source

Self-powered triboelectric nanogenerator sensor for detecting humidity level and monitoring ethanol variation in a simulated exhalation environment

Scientific Reports
Respiration stands as a vital process reflecting physiological and pathological human health status. Exhaled breath analysis offers a facile, non-invasive, swift, and cost-effective approach for diagnosing and monitoring diseases by detecting ...
Nima Mohamadbeigi, Leyla Shooshtari, Somayeh Fardindoost, Mohaddese Vafaiee, Azam Iraji zad, Raheleh Mohammadpour   +5 more
doaj   +1 more source

Advances in Breath Analysis-Based Disease Diagnosis Technology and Standardization Requirements

Zhipu Xuebao
The composition and content of volatile organic compounds (VOCs) in exhaled breath are closely related to change in the human physiological state. Some biosignature molecules generated by human metabolism, including disease marker molecules, are expelled
Wen-quan ZHANG, Lu-lu FENG, Zi-hong YE, Xiao-yun GONG   +3 more
doaj   +1 more source

Feasibility of Thermal Imaging for Contactless Respiratory Monitoring in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim Respiratory rate is a key vital sign in paediatric assessment, but accurate measurement in emergency settings is difficult because conventional methods (manual counting, capnography) can be unreliable or impractical. Respiratory rate is frequently omitted in busy emergency departments.
Takeru Kanazawa, Yoshifusa Abe, Hoang Thi Yen, Guanghao Sun   +3 more
wiley   +1 more source

Story2Board: A Training‐Free Approach for Expressive Visual Storytelling

Computer Graphics Forum, EarlyView.
Abstract We present Story2Board, a training‐free framework for expressive storyboard generation from natural language. Existing methods narrowly focus on subject identity, overlooking key aspects of visual storytelling such as spatial composition, background evolution, and narrative pacing.
D. Dinkevich, M. Levy, O. Avrahami, D. Samuel, D. Lischinski   +4 more
wiley   +1 more source

Parent child contact problems—Re‐connecting the dots through a somatic lens

Family Court Review, EarlyView.
Abstract Parent child contact problems (PCCP) and parental alienation (PA) occupy much time for family law professionals especially as parents might use the term PA loosely, for the parent allegedly doing PA and the parent experiencing PA. Negotiating safety, connection and distance are fundamental to PCCP.
Maureen Mueller
wiley   +1 more source

The role of obstructive sleep apnea syndrome and obesity in determining leptin in the exhaled breath condensate

, 2010
Leptin plays a key role in obstructive sleep apnea syndrome (OSAS). Leptin production in human airways has been previously evaluated by measuring leptin concentration in the exhaled breath condensate and in the induced sputum. The aim was to study leptin
O. Resta, G. De Pergola, CARPAGNANO, GIOVANNA ELISIANA, R. Sabato, FOSCHINO BARBARO, MARIA PIA   +4 more
core   +1 more source