Results 61 to 70 of about 273,434 (312)
Exhaustion of Leisure: Identity and Cycling [PDF]
, 2014 Finn Kolsrud examines amateur bicycling from a sociological perspective, relying on interviews and the concepts of exhaustion and flow. Kolsrud’s project examines the ways that the drive to compete gets mixed with the drive to get ahead.
Finn Kolsrud
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Predicting emotional exhaustion among haemodialysis nurses [PDF]
, 2014 Background\ud \ud Understanding the organisational predictors of burnout (emotional exhaustion) in haemodialysis nurses is critical for staff retention and improving nurse and patient outcomes.
Bonner, Ann +2 more
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Can empathy lead to emotional exhaustion in teachers? The mediating role of emotional labor [PDF]
, 2013 Objectives: The present study was designed to examine the links between empathy, emotional labor (both surface and deep acting), and emotional exhaustion as well as determine if emotional labor mediates the relationship between empathy and emotional ...
Wróbel, Monika, Monika Wróbel
core +1 more source
Prevention of CD8 T Cell Deletion during Chronic Viral Infection
Viruses, 2021 During chronic viral infections, CD8 T cells rapidly lose antiviral and immune-stimulatory functions in a sustained program termed exhaustion. In addition to this loss of function, CD8 T cells with the highest affinity for viral antigen can be physically
David G. Brooks +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Emotional Exhaustion Among Teachers [PDF]
, 1990 The purpose of the researcher was to investigate burnout in teachers of public and private or parochial schools. The independent variables were: (1) type of school, (2) gender, (3) total years of teaching experience, and (4) grade level assignment.
Kim, Jinhee L.
core +1 more source
Dasatinib is a potent enhancer for CAR T cell generation by CD3-targeted lentiviral vectors
Molecular Therapy: Methods & Clinical Development, 2023 CD3-targeted lentiviral vectors (CD3-LVs) mediate selective transduction of human T lymphocytes in vitro and in vivo while simultaneously activating the targeted cells.
Angela H. Braun +3 more
doaj +1 more source