Results 101 to 110 of about 1,638,815 (287)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Existence and non-existence of solutions for a singular problem with variable potentials

open access: yesElectronic Journal of Differential Equations, 2017
The purpose of this article is to prove some existence and nonexistence theorems for the inhomogeneous singular Dirichlet problem $$ - \Delta_p u = \frac{\lambda k(x)}{u^\delta}\pm h(x) u^q.
Kamel Saoudi
doaj  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Existence and stability of solutions to nonlinear impulsive differential equations in beta-normed spaces

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we consider nonlinear impulsive differential equations in beta-normed spaces. We give new concepts of beta-Ulam's type stability. Also we present sufficient conditions for the existence of solutions for impulsive Cauchy problems ...
Jinrong Wang, Yuruo Zhang
doaj  

A Note on Approximate Hadamard Matrices [PDF]

open access: yesarXiv
A Hadamard matrix is a scaled orthogonal matrix with $\pm 1$ entries. Such matrices exist in certain dimensions: the Hadamard conjecture is that such a matrix always exists when $n$ is a multiple of 4. A conjecture attributed to Ryser is that no circulant Hadamard matrices exist when $n > 4$.
arxiv  

Local criteria for the existence of an accelerated frame of reference [PDF]

open access: yesarXiv, 2002
A local criteria for the existence of an accelerated frame of reference is found. An accelerated frame of reference could exist in all regions where a non-null (non-isotropic) vector field does not degenerate in a null (isotropic) vector field.
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy