Results 101 to 110 of about 8,396,811 (368)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
The Existence of God and the Existence of Homer
Faith and Philosophy, 2002 Can a convincing case be made for the claim that a good God has revealed something to us? We are not asking whether religious belief is rational, or might be properly basic. We are rather asking the question the unconvinced demand be confronted. The standard way of arguing the affirmative creates a huge, unnecessary problem by tacitly presupposing that
Menssen, Sandra, Sullivan, Thomas D.
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Hot Super-Earths with Hydrogen Atmospheres: A Model Explaining Their Paradoxical Existence [PDF]
, 2020 Darius Modirrousta‐Galian +3 more
openalex +1 more source
Linear Pantographic Sheets: Existence and Uniqueness of Weak Solutions
Journal of elasticity, 2017 The well-posedness of the boundary value problems for second gradient elasticity has been studied under the assumption of strong ellipticity of the dependence on the second placement gradients (see, e.g., Chambon and Moullet in Comput. Methods Appl. Mech.
V. Eremeyev +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Event of Faith: The Transformation of Philosophy by Theology in Rudolf Bultmann
Open Theology, 2019 This article suggests that Rudolf Bultmann can be seen to reconfigure Heidegger’s understanding of the relationship between philosophy and theology in terms of a transformation of philosophy by theology. In that sense, though Bultmann is often understood
Deketelaere Nikolaas
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Hyers–Ulam stability and existence criteria for coupled fractional differential equations involving p-Laplacian operator [PDF]
, 2018 Hasib Khan +4 more
openalex +1 more source