Results 121 to 130 of about 8,500,141 (367)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Advances in Nonlinear AnalysisLet Ω⊂Rn\Omega \subset {{\bf{R}}}^{n} be a smooth bounded domain. In this article, we prove a result of which the following is a by-product: Let q∈]0,1[q\in ]0,1{[}, α∈L∞(Ω)\alpha \in {L}^{\infty }\left(\Omega ), with α>0\alpha \gt 0, and k∈Nk\in {\bf{N}}
Ricceri Biagio
doaj +1 more source
, 2022 Giving back life to abandoned traditional montenegrian houses. Saving cultural heritage from vanishing by giving them purpose and making them attractive for the coming generations. The purpose is going to be based on local food production and local arts and crafts.
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Space-dependent variable-order time-fractional wave equation: Existence and uniqueness of its weak solution [PDF]
, 2022 Karel Van Bockstal +2 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The existence of special orthonormal frames [PDF]
, 1968 J. E. D’Atri, Hoffman Nickerson
openalex +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Exploring the Lives of Women Rag Pickers in an Indian Metropolitan City: A Mixed-Methods Cross-Sectional Study on Social and Occupational Determinants Shaping Their Existence [PDF]
, 2023 Swati Iyer +5 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source