Results 161 to 170 of about 7,948,884 (384)
IX. On the discovery of a novel type flint implements below the base of the Red Crag of Suffolk, proving the existence skilled workers of flint in the Pliocene age [PDF]
, 1912 Ray Lankester
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Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
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XV.—The Ontological Argument for the Existence of God [PDF]
, 1918 Albert A. Cock
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Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
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The evidence for the Existence of Man in the Tertiary Period [PDF]
, 1897 E.T. Newton
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Royal Institute of Philosophy Supplement, 2002 It seems obvious that I could have failed to exist. My parents could easily never have met, in which case I should never have been conceived and born. The like applies to everyone. More generally, it seems plausible that whatever exists in space and time could have failed to exist. Events could have taken an utterly different course.
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Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
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, 2022 Giving back life to abandoned traditional montenegrian houses. Saving cultural heritage from vanishing by giving them purpose and making them attractive for the coming generations. The purpose is going to be based on local food production and local arts and crafts.
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