Results 51 to 60 of about 6,496,822 (268)
Certifying the Existence of Epipolar Matrices [PDF]
, 2014 Given a set of point correspondences in two images, the existence of a fundamental matrix is a necessary condition for the points to be the images of a 3-dimensional scene imaged with two pinhole cameras.
Agarwal, Sameer +3 more
core
Existence and non existence of capillary surfaces
Manuscripta Mathematica, 1979 A general criterion for existence of solutions of the capillary equation, introduced by Concus and Finn [1] and by Giusti [7], is shown to be equivalent to the question of existence of certain vector fields. The result is applied to particular boundary configurations, and it is shown that in some cases the local “corner condition” of [1] is both ...
openaire +3 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Ethical Theory and Moral Practice, 2017 Can existence benefit or harm a person? I argue that it cannot. In order for existence to harm a person it has to be the case that existence is worse for the person than never existing. This claim could only be true if it is understood as a claim about the actual, extrinsic value of existence for a person.
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Pre-Existence and Post-Existence of Thought [PDF]
Nature, 1885 To express any views on these subjects one might well have hesitated some years ago, as hereditary transmission, tolerated as a doctrine, chiefly with regard to the breeding of sheep and dogs, was held to be unphilosophical. Darwin has settled the matter in the domain of science, but perhaps without altogether disposing of prejudices. Mr.
openaire +3 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source