Results 81 to 90 of about 6,731,721 (317)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

On existence of log minimal models

open access: yes, 2009
In this paper, we prove that the log minimal model program in dimension $d-1$ implies the existence of log minimal models for effective lc pairs (eg of nonnegative Kodaira dimension) in dimension $d$.
Caucher Birkar   +7 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

On the existence of maximal orders

open access: yes, 2011
We generalize the existence of maximal orders in a semi-simple algebra for general ground rings. We also improve several statements in Chapter 5 and 6 of Reiner's book concerning separable algebras by removing the separability condition, provided the ...
Yu, Chia-Fu
core   +1 more source

Existence of non-oscillatory solutions to higher-order mixed difference equations

open access: yesElectronic Journal of Differential Equations, 2007
In this paper, we consider the higher order neutral nonlinear difference equation$$displaylines{ Delta^{m}(x(n)+p(n)x(au(n)))+f_1(n,x(sigma_{1}(n))) -f_2(n,x(sigma_{2}(n)))=0, cr Delta^{m}(x(n)+p(n)x(au(n)))+f_1(n,x(sigma_{1}(n))) -f_2(n,x(sigma_{2}(n)))=
Qiaoluan Li   +3 more
doaj  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Existence of solutions to Burgers equations in a non-parabolic domain

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we study the semilinear Burgers equation with time variable coefficients, subject to boundary condition in a non-parabolic domain. Some assumptions on the boundary of the domain and on the coefficients of the equation will be imposed.
Yassine Benia, Boubaker-Khaled Sadallah
doaj  

Existence and non existence of capillary surfaces

open access: yesManuscripta Mathematica, 1979
A general criterion for existence of solutions of the capillary equation, introduced by Concus and Finn [1] and by Giusti [7], is shown to be equivalent to the question of existence of certain vector fields. The result is applied to particular boundary configurations, and it is shown that in some cases the local “corner condition” of [1] is both ...
openaire   +3 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

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