Results 111 to 120 of about 12,609 (311)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Existence and Uniqueness of the Solution of Lorentz-Rössler Systems with Random Perturbations
Abstract and Applied Analysis, 2013 We consider a new chaotic system based on merging two well-known systems (the Lorentz and Rössler systems). Meanwhile, taking into account the effect of environmental noise, we incorporate whit-enoise in each equation. We prove the existence, uniqueness,
Xiaoying Wang, Fei Jiang, Junping Yin
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Existence and Uniqueness of The Solution of Nonlinear Volterra Fuzzy Integral Equations
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 In this paper, we proved the existence and uniqueness of the solution of nonlinear Volterra fuzzy integral equations of the second kind.
Eman A. Hussain, Ayad W. Ali
doaj
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Journal of Fixed Point Theory and Applications, 2019 E. Hernández +2 more
semanticscholar +1 more source
Unique existence, approximate solutions, and countable choice
Theoretical Computer Science, 2003 The author investigates the use of the principle of countable choice in proofs of constructive mathematics. The author has the following two theses (which are not mathematical theorems) about constructive proofs: 1) Constructions of uniquely determined solutions presumably do not require choice; 2) approximate mathematics is closely related with choice-
openaire +2 more sources