Results 101 to 110 of about 12,609 (311)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Pseudo almost periodic solutions to some differential equations with infinite delay
Electronic Journal of Differential Equations, 2006 This paper studies some sufficient conditions for the existence and uniqueness of a pseudo almost periodic mild solution to abstract hyperbolic differential equations with infinite delay.
Toka Diagana
doaj
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Existence and uniqueness of analytic solutions of the Shabat equation [PDF]
Abstract and Applied Analysis, 2005 Sufficient conditions are given so that the initial value problem for the Shabat equation has a unique analytic solution, which, together with its first derivative, converges absolutely for z ∈ ℂ : |z| < T, T > 0. Moreover, a bound of this solution is given.
openaire +4 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Existence and uniqueness of equilibrium states of a rotating elastic rod
International Journal of Mathematics and Mathematical Sciences, 1994 A flexible rod is rotated from one end. The equilibrium equation is a fourth order nonlinear two-point boundary value problem which depends on two parameters λ and α representing the importance of centrifugal effects to flexural rigidity and the angle ...
M. B. M. Elgindi
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Electronic Journal of Differential Equations, 2014 In this article we study the existence, uniqueness and asymptotic stability of solution to the mixed problem for the semilinear wave equation with acoustic boundary conditions in domains with non-locally reacting boundary.
Cicero L. Frota +2 more
doaj
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source