Results 71 to 80 of about 251,787 (265)

An Existence Result for Neutral Delay Integrodifferential Equations with Fractional Order and Nonlocal Conditions

Abstract and Applied Analysis, 2011
We study the existence of mild solutions of a class of neutral delay integrodifferential equations with fractional order and nonlocal conditions in a Banach space X. An existence result on the mild solution is obtained by using the theory of the measures
Fang Li, Gaston M. N'Guérékata
doaj   +1 more source

Sadraean Analysis of Prophetic Traditions regarding Essential Monotheism Emphasizing the works of Ayatollah Javadi Amoli [PDF]

حکمت اسرا
The Foremost of the Theosophers (Sadr Al-Din Shirazi) the founder of philosophical school of Hikmat Al-Mutalyah has invented the theory of related existence of the effect in the analysis of the issue of the relation between the essentially necessary ...
Hasan Mohseni, Mohammadreza Mostafapour, Behroz Mohammadimonfared   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A Muslim Contribution to International Relations Theory: Aman (Peaceful Co-Existence and Mutual Respect) Theory

Journal of International Studies, 2020
In the last ten years, the world has witnessed much debate on new forms of the global phenomena of fundamentalism and extremism. It is clear that many view Muslims as “the other” or outsider and vice-versa; an attitude of “us and them”, “our ...
Abd al-Fattah M. El-Awaisi
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Existence theory for functional initial value problems of ordinary differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2004
In this paper the existence of a solution of general nonlinear functional differential equations is proved under mixed generalized Lipschitz and Carath\'eodory condition.
Bapurao Dhage
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Existence theory and numerical analysis of three species prey-predator model under Mittag-Leffler power law. [PDF]

Adv Differ Equ, 2020
Abdo MS, Panchal SK, Shah K, Abdeljawad T.   +3 more
europepmc   +1 more source