Results 101 to 110 of about 22,124,873 (289)

Phenomenological method in humanistic and existential psychotherapy

Консультативная психология и психотерапия, 2012
The present article is a result of a comparative analysis of phenomenological practice in five psychotherapeutic ap-proaches - gestalt –therapy, person-centered therapy, focusing-oriented therapy, British school of existential analysis and Austrian ...
Evstigneeva E.A.
doaj  

Existential feelings and the feeling of pastness in episodic remembering

Filosofia Unisinos
In this paper, I propose a collaborative approach to analysing the phenomenal experience of episodic remembering, bringing together contemporary phenomenology of existential feelings with metacognitive approaches to the feeling of pastness.
Robson Ramos Reis
doaj   +1 more source

Materialisation of existential aesthetics

, 2023
Maes’ proposal on existential aesthetics, which appeared in the Journal of Aesthetics and Art Criticism in 2022, has the potential to be extended in myriad manners. Here, the attempt is to confer a material or tangible extension to his proposal. Material
Khetrapal, Neha
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Query answering over disjunctive datalog with existential quantifiers [PDF]

The paper discusses the impact of adding existential quantifi- cation in the head of positive disjunctive Datalog rules. After introducing syntax and semantics of the resulting language, we provide a notion of instantiation, which has been proven to ...
Alviano, Mario, Faber, Wolfgang, Leone, Nicola, Manna, Marco   +3 more
core   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A Systemic-Functional Linguistic Analysis of Saki’s “The Image of the Lost Soul”

Qubahan Academic Journal
This paper used Systemic-Functional Linguistics (SFL) to analyze Saki's short story “The Image of the Lost Soul” through Halliday's transitivity framework to reveal the linguistic methods of creating emotional detachment and existential loneliness with ...
Howard Aries Ronquillo
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Existential Counselling Primer

, 2012
A brief, accessible introduction to the theory and practice of existential counselling and ...
Cooper, Mick
core   +2 more sources