Results 81 to 90 of about 197,200 (292)
Existential Therapy within Palliative Care: Searching for Meaning
European PsychiatryIntroduction Irvin D. Yalom defines existential psychotherapy as a dynamic therapeutic approach that focuses on concerns rooted in existence with the four ultimate concerns being death, isolation, meaning in life, and freedom.
F. Cunha +8 more
doaj +1 more source
Pakistan’s Nuclear Weapons Program and Implications for US National Security. [PDF]
, 2010 This article analyzes Pakistan’s nuclear weapons program and the characteristics of the environment in which the program is nested. These characteristics include Pakistan’s history of internal and external instability; nuclear saber rattling during ...
Tkacik, Michael
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Memorability of Supernatural Concepts: Effects of Minimal Counterintuitiveness, Moral Valence, and Existential Anxiety on Recall [PDF]
Within the cognitive science of religion, some scholars hypothesize (1) that minimally counterintuitive (MCI) concepts enjoy a transmission advantage over both intuitive and highly counterintuitive concepts, (2) that religions concern counterintuitive ...
Beebe, James R., Duffy, Leigh
core
The Relevance of an Existential Conception of Nature [PDF]
, 2014 It is often assumed that science provides the most accurate knowledge about nature. This view not only collapses distinctions between different forms of knowing but also results in a paradox whereby understanding what it means to exist in the world is ...
Mei, Todd
core +1 more source
Loss of trust as disconnection in John Updike’s Trust me. [PDF]
, 2012 While the title of John Updike’s short-story collection, Trust Me (1987), and the theme of betrayed trust of the first story (“Trust Me”) offer a thematic coherence to the collection, it would be restrictive to read the stories through the simple ...
Duffy, Brian
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Space Colonization and Existential Risk [PDF]
, 2019 Ian Stoner has recently argued that we ought not to colonize Mars because doing so would flout our pro tanto obligation not to violate the principle of scientific conservation, and there is no countervailing considerations that render our violation of ...
Gottlieb, Joseph
core
Externalism, internalism and logical truth [PDF]
, 2009 The aim of this paper is to show what sorts of logics are required by externalist and internalist accounts of the meanings of natural kind nouns. These logics give us a new perspective from which to evaluate the respective positions in the externalist ...
Besson, Corine
core +1 more source
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source